Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5566059 | 0.85 | LMNA (0.44) | KDRACHEALDH1A1KDM4ERAB9A | |
| Hydrochloric Acid SCHEMBL5565982 | 0.76 | ALDH1A1 (0.40) | KDRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL7555415 | 0.75 | HPGD (0.54) | KDRALDH1A1MEN1CYP3A4GAA | |
| Hydrochloric Acid SCHEMBL6130211 | 0.73 | TUBB4A (0.45) | ALDH1A1KDM4ERAB9A | |
| Hydrochloric Acid SCHEMBL21328515 | 0.71 | ACHE (0.61) | ACHEBCHEALDH1A1CHKAKDM4E | |
| Hydrochloric Acid SCHEMBL5565999 | 0.71 | KDR (0.41) | KDRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL17508259 | 0.69 | TDP1 (0.56) | KDRRAPGEF4ALDH1A1KDM4EMEN1 | |
| SCHEMBL22422901 | 0.69 | ACHE (0.63) | ACHEBCHEALDH1A1CHKA | |
| SCHEMBL5564793 | 0.69 | KDR (0.40) | KDRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL9432804 | 0.68 | BCHE (0.53) | ACHEBCHEALDH1A1CHKAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7229479-B2 | Method of coloring porous material | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-06-12 | — | — | US | disclosed |
| US-20060162095-A1 | Method of colouring porous material | CIBA SPECIALTY CHEMICALS CORP. | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060162095-A1 | Method of colouring porous material | ACR, HLA-C, TYR | ACHE 1932/4885KDR 4077/4885BCHE 2169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.