Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CENPE | Q02224 | 2/20 | 0.37 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 12/20 | 0.34 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2104386 | 0.82 | CENPE (0.42) | CENPEKIFC1S1PR1WDR5P2RX3 | |
| SCHEMBL4722945 | 0.81 | CENPE (0.38) | CENPEKIFC1S1PR1WDR5P2RX3 | |
| SCHEMBL2630625 | 0.80 | CENPE (0.41) | CENPEKIFC1S1PR1KMOWDR5 | |
| SCHEMBL2105714 | 0.77 | KIFC1 (0.38) | CENPEKIFC1S1PR1KMOWDR5 | |
| SCHEMBL4835982 | 0.75 | CENPE (0.46) | CENPEKIFC1S1PR1KMOWDR5 | |
| SCHEMBL13456835 | 0.74 | CENPE (0.37) | CENPEKIFC1S1PR1KMOWDR5 | |
| SCHEMBL2104984 | 0.69 | CENPE (0.41) | CENPEKIFC1S1PR1KMOP2RX3 | |
| SCHEMBL2104183 | 0.69 | CENPE (0.40) | CENPEKIFC1S1PR1KMOWDR5 | |
| SCHEMBL2104482 | 0.68 | HPSE (0.46) | — | |
| SCHEMBL2105148 | 0.68 | CENPE (0.40) | CENPEKIFC1S1PR1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070149516-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INCORPORATED | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149516-A1 | Certain chemical entities, compositions, and methods | KIF5B, KIF2C, PLK1 | CENPE 54/4885KIFC1 4/4885S1PR1 2943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.