Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3251429 | 0.77 | ALDH1A1 (0.36) | SLC6A4SLC6A3HPRT1ALDH1A1TSHR | |
| SCHEMBL1363490 | 0.77 | IMPDH2 (0.52) | ALDH1A1KDM4EIMPDH2IMPDH1GAA | |
| SCHEMBL737625 | 0.77 | SLC6A4 (0.33) | SLC6A4SLC6A3HPRT1ALDH1A1TSHR | |
| SCHEMBL30366540 | 0.77 | HPRT1 (0.46) | SLC6A4SLC6A3HPRT1ALDH1A1TSHR | |
| SCHEMBL6562728 | 0.77 | HPRT1 (0.46) | SLC6A4SLC6A3HPRT1ALDH1A1TSHR | |
| SCHEMBL737681 | 0.71 | HTT (0.37) | ALDH1A1TSHRL3MBTL1FABP4HTT | |
| SCHEMBL208029 | 0.70 | — | — | |
| SCHEMBL18244829 | 0.70 | ALDH1A1 (0.44) | HPRT1ALDH1A1TSHR | |
| SCHEMBL16917822 | 0.69 | HTR1B (0.42) | SLC6A4SLC6A3HPRT1ALDH1A1TSHR | |
| SCHEMBL18245251 | 0.69 | CES2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847545-B1 | SUBSTITUTED ETHYNYL GOLD-NITROGENATED HETEROCYCLIC CARBENE COMPLEX AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | UBE INDUSTRIES (JP) | 2013-03-06 | — | — | EP | disclosed |
| EP-1847545-A1 | SUBSTITUTED ETHYNYL GOLD-NITROGENATED HETEROCYCLIC CARBENE COMPLEX AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | Ube Industries, Ltd. (JP) | 2007-10-24 | — | — | EP | disclosed |