Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 12/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPN | P05981 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5576957 | 0.90 | VCAM1 (0.41) | VCAM1GAANPSR1 | |
| SCHEMBL5574359 | 0.88 | VCAM1 (0.47) | VCAM1HPNMAPTALOX15SIRT5 | |
| SCHEMBL5574398 | 0.82 | VCAM1 (0.61) | VCAM1HPNMAPTALOX15SIRT5 | |
| SCHEMBL5575971 | 0.81 | VCAM1 (0.41) | VCAM1HPNMAPTALOX15SIRT5 | |
| SCHEMBL5138217 | 0.81 | VCAM1 (0.39) | VCAM1NPSR1ALOX15 | |
| SCHEMBL5576955 | 0.75 | ALOX15 (0.37) | VCAM1HPNMAPTALOX15SIRT5 | |
| SCHEMBL6274260 | 0.74 | VCAM1 (0.41) | VCAM1GAANPSR1PKMHTT | |
| SCHEMBL6274329 | 0.74 | VCAM1 (0.41) | VCAM1GAANPSR1PKMHTT | |
| SCHEMBL29844088 | 0.73 | NLRP3 (0.44) | GAANPSR1SMN1; SMN2MAPTNLRP3 | |
| SCHEMBL5574203 | 0.72 | VCAM1 (0.58) | VCAM1GAANPSR1HPNMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7271274-B2 | Phenolic antioxidants for the treatment of disorders including arthritis, asthma and coronary artery disease | AHTEROGENICS, INC. (US) | 2007-09-18 | — | — | US | disclosed |
| US-20060020038-A1 | Phenolic antioxidants for the treatment of disorders including arthritis, asthma and coronary artery disease | CRABTREE ACQUISITION CO, LLC | 2006-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060020038-A1 | Phenolic antioxidants for the treatment of disorders including arthritis, asthma and coronary artery disease | MPO, ALOX15B, ALOX12 | VCAM1 961/4885GAA 589/4885NPSR1 2078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.