SCHEMBL557566

SCHEMBL557566

CCO[Si](CN1CCNCC1)(OCC)OCC

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
POLB P06746 1/20 0.32
CXCR4 P61073 2/20 0.31
CHRM5 P08912 1/20 0.31
CHRM3 P20309 1/20 0.31
CYP1A2 P05177 2/20 0.30
CYP2D6 P10635 1/20 0.30
CHRM2 P08172 1/20 0.30
SLC6A4 P31645 1/20 0.30
OPRD1 P41143 1/20 0.30
OPRK1 P41145 1/20 0.30
LMNA P02545 1/20 0.30
DRD2 P14416 1/20 0.30
DRD3 P35462 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1519033 0.98 CYP1A2 (0.33) SIGMAR1SMN1; SMN2POLBCXCR4CHRM5
SCHEMBL2380462 0.88
SCHEMBL2385305 0.84
SCHEMBL2384105 0.84
SCHEMBL4002631 0.82 SIGMAR1 (0.33) SIGMAR1SMN1; SMN2POLBCXCR4CHRM5
SCHEMBL538138 0.82 SIGMAR1 (0.36) SIGMAR1SMN1; SMN2POLBCXCR4CHRM5
SCHEMBL2383064 0.80 ALDH1A1 (0.30)
SCHEMBL2381809 0.80
SCHEMBL4005712 0.80 SIGMAR1 (0.35) SIGMAR1SMN1; SMN2POLBCYP1A2CHRM2
SCHEMBL4061260 0.80 POLB (0.38) SIGMAR1SMN1; SMN2POLBCXCR4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7569691-B2 Protected piperazino group-bearing organoxysilane compound and making method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-08-04 US claimed
US-12545809-B2 Moisture-curing conformal coating compositions WACKER CHEMIE AG (DE) 2026-02-10 US disclosed
WO-2025223681-A1 CROSS-LINKABLE COMPOSITIONS ON THE BASIS OF ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2025-10-30 WO disclosed
EP-4499747-B1 CROSS-LINKABLE COMPOSITIONS ON THE BASIS OF ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2025-10-29 EP disclosed
US-12448487-B2 Polysiloxanes with radiation- and moisture-cross-linkable groups WACKER CHEMIE AG (DE) 2025-10-21 US disclosed
US-20250215158-A1 Cross-linkable compositions on the basis of organosilicon compounds WACKER CHEMIE AG (DE) 2025-07-03 US disclosed
EP-4499747-A1 CROSS-LINKABLE COMPOSITIONS ON THE BASIS OF ORGANOSILICON COMPOUNDS Wacker Chemie AG (DE) 2025-02-05 EP disclosed
CN-118974157-A Crosslinkable compositions based on organosilicon compounds 瓦克化学股份公司 2024-11-15 CN disclosed
EP-4172246-B1 MOISTURE-CURING CONFORMAL COATING COMPOSITIONS WACKER CHEMIE AG (DE) 2024-08-07 EP disclosed
CN-115397891-B Polysiloxanes with radiation-crosslinkable and moisture-crosslinkable groups 瓦克化学股份公司 2024-02-02 CN disclosed
CN-1950458-A Moisture cross-linking composition containing alkoxysilyl functional particles CONSORTIUM ELEKTROCHEM IND (DE) 2007-04-18 CN disclosed
EP-1745107-A2 MOISTURE CROSS-LINKING COMPOSITION CONTAINING ALKOXYSILYL FUNCTIONAL PARTICLES Consortium für elektrochemische Industrie GmbH (DE) 2007-01-24 EP disclosed
US-20060258820-A1 Process for preparing dispersions of crosslinked organopolysiloxanes WACKER CHEMIE AG (DE) 2006-11-16 US disclosed
WO-2006119916-A1 METHOD FOR PRODUCING CROSSLINKABLE ORGANOPOLYSILOXANE DISPERSIONS WACKER CHEMIE AG (DE) 2006-11-16 WO disclosed
EP-1721926-A1 Process for the production of dispersions of cross linked organopolysiloxanes Wacker Chemie AG (DE) 2006-11-15 EP disclosed
US-20060241294-A1 Protected piperazino group-bearing organoxysilane compound and making method SHIN-ETSU CHEMICAL CO., LTD. 2006-10-26 US disclosed
EP-1714968-A1 Protected piperazino group-bearing organoxysilane compound and making method Shin-Etsu Chemical Co., Ltd. (JP) 2006-10-25 EP disclosed
WO-2006061091-A2 HIGHLY REACTIVE $G(A)-AMINOMETHYL-ALKOXYSILANES HAVING IMPROVED STABILITY WACKER CHEMIE AG (DE) 2006-06-15 WO disclosed
WO-2006061090-A1 ALKOXYSILANE-TERMINATED PREPOLYMERS WACKER CHEMIE AG (DE) 2006-06-15 WO disclosed
WO-2005108495-A2 MOISTURE CROSS-LINKING COMPOSITION CONTAINING ALKOXYSILYL FUNCTIONAL PARTICLES Consortium für elektrochemische Industrie GmbH (DE) 2005-11-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060241294-A1 Protected piperazino group-bearing organoxysilane compound and making method PIEZO1, VCL, VIM SIGMAR1 1050/4885SMN1; SMN2 1719/4885POLB 1859/4885
US-12545809-B2 Moisture-curing conformal coating compositions COL1A1, COL2A1, MSR1 SIGMAR1 42/4885SMN1; SMN2 181/4885POLB 2336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.