Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5495749 | 0.79 | — | — | |
| SCHEMBL79520 | 0.79 | KDM4E (0.36) | ALDH1A1CA1CA2MEN1KMT2A | |
| SCHEMBL7931609 | 0.77 | CYP2C19 (0.33) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL6887707 | 0.74 | CA12 (0.48) | PTPN1ALDH1A1CA12CA1CA2 | |
| SCHEMBL5576207 | 0.73 | PKM (0.40) | ALDH1A1L3MBTL1MEN1KMT2APKM | |
| SCHEMBL9479020 | 0.70 | MT-CO2 (0.50) | ALDH1A1SMN1; SMN2ALOX5KDM4EGAA | |
| SCHEMBL896334 | 0.67 | ALDH1A1 (0.39) | ALDH1A1TSHRL3MBTL1MEN1KMT2A | |
| SCHEMBL1832039 | 0.67 | PKM (0.38) | ALDH1A1L3MBTL1MEN1KMT2APKM | |
| SCHEMBL1834304 | 0.67 | PKM (0.36) | PTPN1ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL2239737 | 0.65 | POLB (0.51) | ALDH1A1L3MBTL1MEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7632816-B2 | Treatment of Alzheimer amyloid deposition | NEW YORK UNIVERSITY (US) | 2009-12-15 | — | — | US | disclosed |
| US-20040214774-A1 | Prevention and treatment of Alzheimer amyloid deposition | NEW YORK UNIVERSITY | 2004-10-28 | — | — | US | disclosed |