Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.49 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.49 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577476 | 0.85 | LMNA (0.55) | MEN1KMT2ACHRM3SMN1; SMN2BCHE | |
| SCHEMBL5577583 | 0.83 | CCR3 (0.55) | MEN1KMT2ACHRM4DRD4CXCR3 | |
| SCHEMBL6358889 | 0.81 | ALDH1A1 (0.65) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5577369 | 0.80 | MAPT (0.57) | MEN1KMT2ACHRM4ACKR3 | |
| SCHEMBL5577828 | 0.79 | POLB (0.53) | MEN1KMT2A | |
| SCHEMBL5577829 | 0.77 | SIGMAR1 (0.51) | MEN1KMT2ACHRM3SLC6A12 | |
| SCHEMBL5577706 | 0.77 | PROKR1 (0.52) | MEN1KMT2ACHRM4ACKR3CXCR3 | |
| SCHEMBL5577554 | 0.77 | MT-CO2 (0.55) | MEN1KMT2ACHRM4ACKR3BCHE | |
| SCHEMBL5577650 | 0.77 | MEN1 (0.62) | MEN1KMT2AACHEBACE1 | |
| SCHEMBL5577389 | 0.77 | CHRM3 (0.61) | MEN1KMT2ACHRM4DRD4CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1616862-A1 | NITROGENOUS HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | HLA-DRB1, MIF, HLA-C | MEN1 748/4885KMT2A 3527/4885CHRM4 3794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.