SCHEMBL8912112

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22400033	0.86	HSD17B1 (0.43)	ALDH1A1RAB9ANPC1PAX8KMT2A
	SCHEMBL30880030	0.85	MAPT (0.44)	ALDH1A1NPC1SMN1; SMN2KMT2AMEN1
	SCHEMBL3168456	0.85	MAPT (0.49)	ALDH1A1RAB9ANPC1SMN1; SMN2KMT2A
	SCHEMBL10787316	0.84	ALDH1A1 (0.47)	ALDH1A1RAB9ANPC1PAX8KMT2A
	SCHEMBL10011062	0.84	MTNR1A (0.55)	ALDH1A1LMNAMAPK1MAPTHSD17B1
	SCHEMBL557889	0.83	SMN1; SMN2 (0.55)	ALDH1A1SMN1; SMN2KMT2AMEN1MAPT
	SCHEMBL1120517	0.83	ALDH1A1 (0.43)	ALDH1A1RAB9ANPC1PAX8TP53
	SCHEMBL10785745	0.82	RAB9A (0.45)	ALDH1A1RAB9ANPC1PAX8KMT2A
	Hydrochloric Acid SCHEMBL7150239	0.82	SMN1; SMN2 (0.54)	ALDH1A1SMN1; SMN2KMT2AMEN1MAPT
	SCHEMBL10194297	0.82	ALDH1A1 (0.46)	ALDH1A1RAB9ANPC1PAX8TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.