Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 9/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21536748 | 0.84 | SMN1; SMN2 (0.39) | ALDH1A1CYP1A2HPGDNUDT1HSD17B10 | |
| SCHEMBL16441111 | 0.81 | SMN1; SMN2 (0.37) | ALDH1A1CYP1A2HPGDNUDT1HSD17B10 | |
| SCHEMBL12105229 | 0.79 | SMN1; SMN2 (0.33) | ALDH1A1HPGDHSD17B10SMN1; SMN2ADORA2A | |
| SCHEMBL23513918 | 0.77 | KCNH2 (0.34) | SMN1; SMN2ADORA2BADORA2A | |
| SCHEMBL28386162 | 0.68 | SMN1; SMN2 (0.56) | ALDH1A1CYP1A2HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL30808060 | 0.68 | IKBKB (0.53) | ALDH1A1HPGDHSD17B10MAPTCDC7 | |
| SCHEMBL18312205 | 0.68 | IKBKB (0.53) | ALDH1A1HPGDHSD17B10MAPTCDC7 | |
| SCHEMBL31218404 | 0.68 | SMN1; SMN2 (0.56) | ALDH1A1CYP1A2HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL14871305 | 0.67 | KIT (0.44) | ADORA2BADORA2ACDC7DBF4 | |
| SCHEMBL17339831 | 0.66 | PKM (0.33) | ALDH1A1HPGDHSD17B10SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213305-A1 | N-alkyl-N-aryl-thienopyrimidin-4-amines and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. (US) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213305-A1 | N-alkyl-N-aryl-thienopyrimidin-4-amines and analogs as activators of caspases and inducers of apoptosis and the use thereof | CASP10, CASP4, CASP3 | ALDH1A1 1247/4885CYP1A2 918/4885HPGD 2073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.