Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 2/20 | 0.72 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.72 |
| ▸ | RAB9A | P51151 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.61 |
| ▸ | EGFR | P00533 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | GALR3 | O60755 | 1/20 | 0.59 |
| ▸ | CCNC | P24863 | 1/20 | 0.57 |
| ▸ | CDK8 | P49336 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | PDE5A | O76074 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5423236 | 0.87 | RAB9A (0.73) | TNFNOD1RAB9AMEN1KMT2A | |
| SCHEMBL27697481 | 0.85 | RAB9A (0.64) | TNFNOD1RAB9AMEN1KMT2A | |
| SCHEMBL7404118 | 0.84 | TNF (1.00) | TNFNOD1RAB9AMEN1KMT2A | |
| SCHEMBL3118967 | 0.81 | TNF (0.48) | TNFNOD1RAB9AMEN1KMT2A | |
| SCHEMBL8515605 | 0.77 | KMT2A (0.57) | TNFNOD1RAB9AMEN1KMT2A | |
| SCHEMBL3342319 | 0.77 | CCNC (0.70) | RAB9AMEN1KMT2ANR2F2EGFR | |
| SCHEMBL31217447 | 0.76 | RAB9A (0.61) | TNFNOD1RAB9AMEN1KMT2A | |
| SCHEMBL8496629 | 0.76 | HTT (0.71) | TNFNOD1RAB9AMEN1KMT2A | |
| SCHEMBL3112115 | 0.76 | EGFR (1.00) | RAB9AMEN1KMT2ANPC1NR2F2 | |
| SCHEMBL22862812 | 0.75 | RAB9A (0.72) | TNFNOD1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213305-A1 | N-alkyl-N-aryl-thienopyrimidin-4-amines and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. (US) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213305-A1 | N-alkyl-N-aryl-thienopyrimidin-4-amines and analogs as activators of caspases and inducers of apoptosis and the use thereof | CASP10, CASP4, CASP3 | TNF 3578/4885NOD1 462/4885RAB9A 1368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.