Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.45 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL63623 | 1.00 | CPB2 (0.58) | CPB2CA2ZDHHC7CA1GRIK1 | |
| SCHEMBL5516547 | 1.00 | CPB2 (0.58) | CPB2CA2ZDHHC7CA1GRIK1 | |
| SCHEMBL3454038 | 1.00 | CPB2 (0.58) | CPB2CA2ZDHHC7CA1GRIK1 | |
| SCHEMBL6899785 | 1.00 | CPB2 (0.58) | CPB2CA2ZDHHC7CA1GRIK1 | |
| SCHEMBL25341592 | 1.00 | CPB2 (0.58) | CPB2CA2ZDHHC7CA1GRIK1 | |
| SCHEMBL18531126 | 1.00 | CPB2 (0.58) | CPB2CA2ZDHHC7CA1GRIK1 | |
| SCHEMBL23879492 | 1.00 | CPB2 (0.58) | CPB2CA2ZDHHC7CA1GRIK1 | |
| SCHEMBL571313 | 1.00 | CPB2 (0.58) | CPB2CA2ZDHHC7CA1GRIK1 | |
| SCHEMBL19148651 | 1.00 | CPB2 (0.58) | CPB2CA2ZDHHC7CA1GRIK1 | |
| SCHEMBL29209211 | 1.00 | CPB2 (0.58) | CPB2CA2ZDHHC7CA1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170015659-A1 | Prodrugs of NH-Acidic Compounds | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2017-01-19 | — | — | US | disclosed |
| US-8389508-B2 | Heterocyclic compounds | GLAXO GROUP LIMITED (GB) | 2013-03-05 | — | — | US | disclosed |
| US-20110269738-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2011-11-03 | — | — | US | disclosed |
| US-7220783-B2 | Para-terphenyl compounds | SHIONOGI & CO., LTD. (JP) | 2007-05-22 | — | — | US | disclosed |
| US-7101915-B1 | P-terphenyl compounds | SHIONOGI & CO., LTD. (JP) | 2006-09-05 | — | — | US | disclosed |
| US-7074836-B1 | SUPPRESSION CELL DIFFERENTIATION OF CELL INTO ANTIBODY; SUPPRESS IMMONOGLOBULINS; ANTIALLERGENS | SHIONOGI & CO., LTD. (JP) | 2006-07-11 | — | — | US | disclosed |
| US-20040127495-A1 | Novel para-terphenyl compounds | SHIONOGI & CO., LTD. | 2004-07-01 | — | — | US | disclosed |
| EP-0933346-B1 | NOVEL p-TERPHENYL COMPOUNDS | SHIONOGI & CO (JP) | 2003-12-10 | — | — | EP | disclosed |
| CN-1232443-A | Novel p-terphenyl compounds | SHIONOGI & CO (JP) | 1999-10-20 | — | — | CN | disclosed |
| EP-0933346-A1 | NOVEL p-TERPHENYL COMPOUNDS | SHIONOGI & CO., LTD. (JP) | 1999-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127495-A1 | Novel para-terphenyl compounds | FCGR3B, FCGR2A, FCGRT | CPB2 3140/4885CA2 3921/4885ZDHHC7 658/4885 |
| US-20110269738-A1 | COMPOUNDS | CYP11B2, CYP11B1, GPR119 | CPB2 1679/4885CA2 2217/4885ZDHHC7 2061/4885 |
| US-20170015659-A1 | Prodrugs of NH-Acidic Compounds | SI, NAAA, NIT2 | CPB2 1201/4885CA2 205/4885ZDHHC7 1490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.