Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 16/20 | 0.40 |
| ▸ | DRD2 | P14416 | 5/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7283546 | 0.89 | HTR1A (0.40) | HTR1ADRD2PRCP | |
| SCHEMBL7283540 | 0.89 | HTR1A (0.40) | HTR1ADRD2PRCP | |
| SCHEMBL7986246 | 0.81 | PRCP (0.44) | HTR1ADRD2PRCP | |
| SCHEMBL28236427 | 0.80 | PRCP (0.43) | HTR1ADRD2PRCP | |
| SCHEMBL26717721 | 0.79 | LMNA (0.34) | DRD2 | |
| SCHEMBL5580304 | 0.77 | HTR1A (0.44) | HTR1ADRD2PRCP | |
| SCHEMBL274434 | 0.76 | DRD2 (0.47) | HTR1ADRD2 | |
| SCHEMBL9824110 | 0.76 | DRD2 (0.47) | HTR1ADRD2 | |
| SCHEMBL274433 | 0.76 | DRD2 (0.47) | HTR1ADRD2 | |
| SCHEMBL9824113 | 0.76 | DRD2 (0.47) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4600777-A | Method of preparing 1-alkyl-7-oxodecahydroquinolines, and cis(±) and tran(±)isomers so prepared | ELI LILLY AND COMPANY (US) | 1986-07-15 | — | — | US | claimed |
| EP-0172697-B1 | Octahydro-oxazolo[4,5-g]quinolines | ELI LILLY AND COMPANY (US) | 1991-09-25 | — | — | EP | disclosed |
| US-4698347-A | HYPOTENSIVE AGENTS, ANTIDEPRESSANTS, SEXUAL DISFUNCTION, PARKINSONS DISEASE | ELI LILLY AND COMPANY (US) | 1987-10-06 | — | — | US | disclosed |
| US-4659832-A | REACTING UREA (OR ISOUREA) WITH 6-OXO-BROMO-QUINOLINE | ELI LILLY AND COMPANY (US) | 1987-04-21 | — | — | US | disclosed |
| US-4600777-A | Method of preparing 1-alkyl-7-oxodecahydroquinolines, and cis(±) and tran(±)isomers so prepared | ELI LILLY AND COMPANY (US) | 1986-07-15 | — | — | US | disclosed |
| US-4600777-A | Method of preparing 1-alkyl-7-oxodecahydroquinolines, and cis(±) and tran(±)isomers so prepared | ELI LILLY AND COMPANY (US) | 1986-07-15 | — | — | US | disclosed |
| US-4600777-A | Method of preparing 1-alkyl-7-oxodecahydroquinolines, and cis(±) and tran(±)isomers so prepared | ELI LILLY AND COMPANY (US) | 1986-07-15 | — | — | US | disclosed |
| US-4587336-A | PARKINSON'S DISEASE | ELI LILLY AND COMPANY (US) | 1986-05-06 | — | — | US | disclosed |
| EP-0172697-A2 | Octahydro-oxazolo[4,5-g]quinolines | ELI LILLY AND COMPANY (US) | 1986-02-26 | — | — | EP | disclosed |
| US-4552956-A | DOPAMINE AGONISTS | ELI LILLY AND COMPANY (US) | 1985-11-12 | — | — | US | disclosed |