Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 3/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.44 |
| ▸ | HNF4A | P41235 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | F11 | P03951 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19237016 | 0.89 | CFD (0.50) | CFDPLGPLAUHNF4AMYC | |
| Hydrochloric Acid SCHEMBL20593581 | 0.88 | CFD (0.49) | CFDPLGPLAUHNF4AMYC | |
| SCHEMBL269867 | 0.79 | HNF4A (0.53) | HNF4APPARGMYCHCAR2 | |
| SCHEMBL20946451 | 0.78 | BCAT2 (0.61) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL5580720 | 0.77 | PLAU (0.55) | CFDPLGPLAU | |
| SCHEMBL5581171 | 0.77 | PLAU (0.57) | CFDPLGPLAU | |
| SCHEMBL5581100 | 0.77 | BRD4 (0.49) | PPARG | |
| SCHEMBL7252300 | 0.77 | ACMSD (0.59) | HNF4APTGER1MYCACMSD | |
| SCHEMBL689031 | 0.77 | HNF4A (0.62) | HNF4AMYCACMSD | |
| SCHEMBL5581828 | 0.76 | PLAU (0.52) | CFDPLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148164-A1 | Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto | BIOGEN IDEC MA INC. (US) | 2007-06-28 | — | — | US | disclosed |