Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 8/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | KDM4B | O94953 | 1/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.38 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049330 | 0.86 | VCAM1 (0.47) | VCAM1TDP1TSHRMAPK1ALDH1A1 | |
| SCHEMBL6901152 | 0.84 | TXNRD1 (0.46) | VCAM1TDP1TSHRMAPK1TXNRD1 | |
| SCHEMBL272834 | 0.83 | TDP1 (0.62) | VCAM1TDP1TSHRMAPK1ALDH1A1 | |
| SCHEMBL6477389 | 0.80 | VCAM1 (0.42) | VCAM1TDP1TSHRALDH1A1MEN1 | |
| SCHEMBL7272261 | 0.80 | ALDH1A1 (0.42) | VCAM1TDP1TSHRMAPK1ALDH1A1 | |
| SCHEMBL1115822 | 0.79 | TDP1 (0.62) | VCAM1TDP1TSHRMAPK1ALDH1A1 | |
| SCHEMBL30946523 | 0.78 | TDP1 (0.59) | VCAM1TDP1TSHRMAPK1ALDH1A1 | |
| SCHEMBL672105 | 0.78 | TDP1 (0.59) | VCAM1TDP1TSHRMAPK1ALDH1A1 | |
| SCHEMBL16838198 | 0.78 | GPR35 (0.52) | TDP1TSHRMAPK1ALDH1A1CA1 | |
| SCHEMBL2145586 | 0.76 | TDP1 (0.69) | VCAM1TDP1TSHRMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7301049-B2 | Photolabile esters and their uses | THE INSTITUTE OF CANCER RESEARCH (GB) | 2007-11-27 | — | — | US | disclosed |
| US-20040242653-A1 | Photolabile esters and their uses | THE INSTITUTE OF CANCER RESEARCH (GB) | 2004-12-02 | — | — | US | disclosed |
| EP-1399412-A1 | PHOTOLABILE ESTERS AND THEIR USES | The Institute of Cancer Research (GB) | 2004-03-24 | — | — | EP | disclosed |
| WO-2003000644-A1 | PHOTOLABILE ESTERS AND THEIR USES | THE INSTITUTE OF CANCER RESEARCH (GB) | 2003-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242653-A1 | Photolabile esters and their uses | DIMT1, DCTD, DTYMK | VCAM1 4454/4885TDP1 177/4885TSHR 1938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.