SCHEMBL6901152

SCHEMBL6901152

O=Cc1c([N+](=O)[O-])ccc([N+](=O)[O-])c1[N+](=O)[O-]

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TXNRD1 Q16881 1/20 0.46
TXNRD3 Q86VQ6 1/20 0.46
TXNRD2 Q9NNW7 1/20 0.46
TSHR P16473 4/20 0.44
GPR35 Q9HC97 1/20 0.44
ALDH5A1 P51649 1/20 0.40
ABAT P80404 1/20 0.40
ERN1 O75460 1/20 0.40
VCAM1 P19320 1/20 0.40
TDP1 Q9NUW8 5/20 0.38
CYP3A4 P08684 1/20 0.38
MAPK1 P28482 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ATM Q13315 1/20 0.36
BCHE P06276 1/20 0.36
ACHE P22303 1/20 0.36
CES1 P23141 1/20 0.36
XDH P47989 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5252402 0.84 TSHR (0.45) TXNRD1TXNRD3TXNRD2TSHRGPR35
SCHEMBL16838198 0.84 GPR35 (0.52) TSHRGPR35ALDH5A1ABATERN1
SCHEMBL16838217 0.84 GPR35 (0.52) TXNRD1TXNRD3TXNRD2TSHRGPR35
SCHEMBL5583401 0.84 VCAM1 (0.51) TXNRD1TXNRD3TXNRD2TSHRVCAM1
SCHEMBL10645648 0.81 ALDH1A1 (0.51) TDP1CYP3A4MEN1KMT2A
SCHEMBL3302919 0.78 TSHR (0.56) TXNRD1TXNRD3TXNRD2TSHRGPR35
SCHEMBL272154 0.77 ERN1 (0.57) TSHRGPR35ALDH5A1ABATERN1
SCHEMBL16838211 0.77 ERN1 (0.56) TSHRGPR35ALDH5A1ABATERN1
SCHEMBL4361452 0.77 ERN1 (0.47) TXNRD1TXNRD3TXNRD2TSHRGPR35
SCHEMBL3035803 0.74 ALDH5A1 (0.53) TSHRGPR35ALDH5A1ABATERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1390336-A1 METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) 2004-02-25 EP claimed
WO-2002096849-A1 METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2002-12-05 WO claimed
EP-1390336-A1 METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) 2004-02-25 EP disclosed
WO-2002096849-A1 METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2002-12-05 WO disclosed