Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27723761 | 0.76 | PTGS2 (0.35) | CYP3A4CYP11B2 | |
| SCHEMBL4596976 | 0.69 | PARP1 (0.44) | KDM1A | |
| SCHEMBL4596968 | 0.69 | KDM1A (0.36) | CYP3A4CYP11B2KDM1ACYP17A1CYP11B1 | |
| SCHEMBL4234781 | 0.66 | PRKAB2 (0.53) | KDM1AMAOB | |
| SCHEMBL27723664 | 0.66 | AQP1 (0.36) | TDP2 | |
| SCHEMBL4230938 | 0.65 | PRKAB2 (0.43) | KDM1AMAOB | |
| SCHEMBL2944704 | 0.65 | BCL2L1 (0.48) | CYP11B2CYP11B1MAOB | |
| SCHEMBL19423241 | 0.65 | BCL2L1 (0.48) | CYP11B2CYP11B1MAOB | |
| SCHEMBL4964977 | 0.64 | TDP2 (0.33) | TDP2 | |
| SCHEMBL4713338 | 0.62 | GPBAR1 (0.34) | TDP2CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007509174-A | — | — | 2007-04-12 | — | — | JP | claimed |
| EP-1675840-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2006-07-05 | — | — | EP | claimed |
| WO-2005044812-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | WYETH A CORPORATION OF THE STATE OF DELAWARE (US) | 2005-05-19 | — | — | WO | claimed |