Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 4/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583672 | 0.86 | SCN9A (0.54) | GRM4HDAC6PDGFRAKDRMAPT | |
| SCHEMBL5583729 | 0.85 | PNLIP (0.57) | GRM4PDGFRAKDRMAPTMEN1 | |
| SCHEMBL5583775 | 0.84 | PNLIP (0.58) | GRM4HDAC6MAPTSMN1; SMN2POLB | |
| SCHEMBL5583666 | 0.84 | PNLIP (0.62) | PDGFRAKDRMAPTMEN1KMT2A | |
| SCHEMBL5584061 | 0.84 | PARG (0.60) | GRM4PDGFRAKDRMAPTMEN1 | |
| SCHEMBL5583684 | 0.82 | KDM4E (0.55) | PDGFRAKDRMAPTSMN1; SMN2RAB9A | |
| SCHEMBL29847245 | 0.82 | NPC1 (0.43) | GRM4HDAC6MAPTSMN1; SMN2RAB9A | |
| SCHEMBL5586536 | 0.81 | GRM4 (0.53) | GRM4HDAC6KDRMAPTSMN1; SMN2 | |
| SCHEMBL5583581 | 0.81 | KDR (0.49) | GRM4PDGFRAKDRMAPTSMN1; SMN2 | |
| SCHEMBL14284595 | 0.81 | KDR (0.55) | PDGFRAKDRRAB9AHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1134214-A1 | PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |