SCHEMBL5583775

SCHEMBL5583775

COc1ccnc(C(=O)Nc2ccc(Oc3ccccc3)c(Cl)c2)c1O

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PNLIP P16233 8/20 0.58
STK39 Q9UEW8 2/20 0.58
PARG Q86W56 2/20 0.58
GRM4 Q14833 3/20 0.57
POLB P06746 1/20 0.53
MAPT P10636 2/20 0.50
SMN1; SMN2 Q16637 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
AXL P30530 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5583729 0.93 PNLIP (0.57) PNLIPSTK39PARGGRM4MAPT
SCHEMBL5583666 0.92 PNLIP (0.62) PNLIPSTK39PARGMAPT
SCHEMBL5584061 0.91 PARG (0.60) PNLIPSTK39PARGGRM4MAPT
SCHEMBL5583760 0.88 STK39 (0.56) STK39PARGGRM4SMN1; SMN2AXL
SCHEMBL14284591 0.88 KDM4E (0.52) PNLIPPARGGRM4POLBMAPT
SCHEMBL14284600 0.87 MEN1 (0.53) PNLIPGRM4MAPTSMN1; SMN2HDAC6
SCHEMBL2237038 0.86 RAB9A (0.53) PNLIPPOLBMAPTSMN1; SMN2AXL
SCHEMBL5583625 0.85 STK39 (0.57) STK39PARGMAPTSMN1; SMN2AXL
SCHEMBL5583770 0.85 GRM4 (0.52) GRM4POLBMAPTSMN1; SMN2
SCHEMBL5583592 0.84 GRM4 (0.54) GRM4POLBMAPTSMN1; SMN2HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed