Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 4/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583775 | 0.84 | PNLIP (0.58) | GRM4MAPTSMN1; SMN2HDAC6POLB | |
| SCHEMBL5583592 | 0.81 | GRM4 (0.54) | GRM4KDRMAPTSMN1; SMN2HDAC6 | |
| SCHEMBL5583751 | 0.80 | S1PR4 (0.47) | S1PR1S1PR3KDRMAPTSMN1; SMN2 | |
| SCHEMBL5586513 | 0.79 | KMT2A (0.47) | KDRMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5583817 | 0.79 | MAPT (0.56) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL5583729 | 0.79 | PNLIP (0.57) | GRM4KDRMAPTMEN1KMT2A | |
| SCHEMBL5583666 | 0.78 | PNLIP (0.62) | KDRMAPTMEN1KMT2A | |
| SCHEMBL5583719 | 0.77 | NPC1 (0.53) | KDRMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5584061 | 0.77 | PARG (0.60) | GRM4KDRMAPTMEN1KMT2A | |
| SCHEMBL5583782 | 0.77 | RAB9A (0.57) | MAPTSMN1; SMN2NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1134214-A1 | PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |