SCHEMBL5583729

SCHEMBL5583729

COc1ccc(Oc2ccc(NC(=O)c3nccc(OC)c3O)cc2Cl)cc1

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PNLIP P16233 11/20 0.57
GRM4 Q14833 2/20 0.53
STK39 Q9UEW8 3/20 0.52
PARG Q86W56 2/20 0.52
PDGFRA P16234 2/20 0.51
KDR P35968 2/20 0.51
MEN1 O00255 1/20 0.51
HSPD1 P10809 1/20 0.51
PIK3CA P42336 1/20 0.51
HTT P42858 1/20 0.51
BLM P54132 1/20 0.51
HSPE1 P61604 1/20 0.51
KMT2A Q03164 1/20 0.51
MAPT P10636 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5583666 0.95 PNLIP (0.62) PNLIPSTK39PARGPDGFRAKDR
SCHEMBL5584061 0.94 PARG (0.60) PNLIPGRM4STK39PARGPDGFRA
SCHEMBL5583775 0.93 PNLIP (0.58) PNLIPGRM4STK39PARGMAPT
SCHEMBL5583823 0.88 PGR (0.55) STK39PARGPDGFRAKDRMAPT
SCHEMBL5583655 0.86 RAB9A (0.53) PNLIPPDGFRAKDRMEN1KMT2A
SCHEMBL14284600 0.86 MEN1 (0.53) PNLIPGRM4PDGFRAKDRMEN1
SCHEMBL5583592 0.85 GRM4 (0.54) GRM4PDGFRAKDRMEN1KMT2A
SCHEMBL14284595 0.83 KDR (0.55) PNLIPPDGFRAKDRMEN1HTT
SCHEMBL5583779 0.83 KDR (0.52) PNLIPSTK39PARGPDGFRAKDR
SCHEMBL14284587 0.83 PDGFRA (0.53) GRM4PDGFRAKDRMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed