Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583578 | 0.85 | SMN1; SMN2 (0.53) | LMNASMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL5583817 | 0.84 | MAPT (0.56) | KLKB1LMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL5583684 | 0.83 | KDM4E (0.55) | LMNASMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL5583581 | 0.82 | KDR (0.49) | KLKB1SMN1; SMN2MAPTALDH1A1RAB9A | |
| SCHEMBL5583672 | 0.82 | SCN9A (0.54) | SMN1; SMN2MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL5583719 | 0.82 | NPC1 (0.53) | LMNASMN1; SMN2MAPTALDH1A1RAB9A | |
| SCHEMBL5583752 | 0.81 | MAPT (0.57) | MAPTRAB9ANPC1KDR | |
| SCHEMBL5583812 | 0.81 | NPC1 (0.64) | LMNASMN1; SMN2MAPTALDH1A1RAB9A | |
| SCHEMBL5583850 | 0.80 | KDR (0.50) | LMNASMN1; SMN2MAPTRAB9ATP53 | |
| SCHEMBL5583655 | 0.80 | RAB9A (0.53) | LMNASMN1; SMN2MAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1134214-A1 | PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |