Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TTK | P33981 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447770 | 0.74 | DCUN1D1 (0.50) | ALDH1A1NPC1GAAHPGDDCUN1D1 | |
| SCHEMBL2819855 | 0.71 | KDM4E (0.48) | RAB9AALDH1A1NPC1POLBKDM4E | |
| SCHEMBL2637845 | 0.67 | PDE10A (0.43) | RAB9AALDH1A1NPC1POLBKDM4E | |
| SCHEMBL4776763 | 0.67 | POLB (0.43) | RAB9AALDH1A1NPC1POLBKDM4E | |
| SCHEMBL5808868 | 0.65 | KDM4E (0.41) | ALDH1A1POLBKDM4EGAAHPGD | |
| SCHEMBL1119445 | 0.64 | CYP3A4 (0.39) | RAB9AALDH1A1NPC1KDM4EIDO1 | |
| Biphenyl SCHEMBL5068276 | 0.61 | ALDH1A1 (0.90) | RAB9AALDH1A1NPC1ATMMAPK1 | |
| SCHEMBL22987201 | 0.57 | L3MBTL1 (0.56) | RAB9AALDH1A1NPC1POLBKDM4E | |
| Anthracene SCHEMBL295636 | 0.57 | ALDH1A1 (0.64) | RAB9AALDH1A1NPC1KDM4EHPGD | |
| Anthracene SCHEMBL3044541 | 0.57 | ALDH1A1 (0.64) | RAB9AALDH1A1NPC1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210024489-A1 | TREATMENT AND PREVENTION OF NEUROPATHIC PAIN WITH P2Y14 ANTAGONISTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2021-01-28 | — | — | US | claimed |
| CN-107531690-B | 4,5,6, 7-tetrahydro-1H-pyrazolo [4,3-c ] pyridin-3-amine compounds as CBP and/or EP300 inhibitors | 基因泰克公司 | 2020-11-06 | — | — | CN | claimed |
| EP-3626717-A1 | SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS | Eisai R&D Management Co., Ltd. (JP) | 2020-03-25 | — | — | EP | claimed |
| EP-2581365-B1 | Heterocyclic compound, organic light-emitting diode comprising the heterocyclic compound, and flat panel display device comprising the organic light-emitting diode | SAMSUNG DISPLAY CO LTD (KR) | 2019-10-16 | — | — | EP | claimed |
| US-RE47193-E1 | Selectively substituted quinoline compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2019-01-08 | — | — | US | claimed |
| US-20180305391-A1 | COFACTOR ANALOGS AS METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2018-10-25 | — | — | US | claimed |
| CN-107531690-A | The amines of 4,5,6,7 tetrahydrochysene 1H pyrazolos [4,3 c] pyridine 3 as CBP and/or EP300 inhibitor | 基因泰克公司 | 2018-01-02 | — | — | CN | claimed |
| WO-2017070464-A1 | COFACTOR ANALOGS AS METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2017-04-27 | — | — | WO | claimed |
| US-20160326161-A1 | SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2016-11-10 | — | — | US | claimed |
| US-9428495-B2 | Selectively substituted quinoline compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2016-08-30 | — | — | US | claimed |
| JP-2003503389-A | — | — | 2003-01-28 | — | — | JP | claimed |
| US-6376490-B1 | STRONG N-METHYL-D-ASPARATE RECEPTOR ANTAGONISTS; USEFUL IN TREATING STROKES, ISCHEMIA, AND CENTRAL NERVOUS SYSTEM INJURIES | PFIZER INC | 2002-04-23 | — | — | US | claimed |
| EP-1194409-A1 | PYRAZOLIDINOL COMPOUNDS | A-Viral AS (NO) | 2002-04-10 | — | — | EP | claimed |
| EP-0885212-B1 | QUINOXALINEDIONES | PFIZER RES AND BR DEV COMPANY (IE) | 2001-11-14 | — | — | EP | claimed |
| WO-2001000585-A1 | PYRAZOLIDINOL COMPOUNDS | A-VIRAL AS (NO) | 2001-01-04 | — | — | WO | claimed |
| JP-3110467-B2 | — | — | 2000-11-20 | — | — | JP | claimed |
| EP-0885212-A1 | QUINOXALINEDIONES | Pfizer Research and Development Company, N.V./S.A. (IE) | 1998-12-23 | — | — | EP | claimed |
| WO-1997032873-A1 | QUINOXALINEDIONES | PFIZER RESEARCH AND DEVELOPMENT COMPANY, N.V./S.A. (IE) | 1997-09-12 | — | — | WO | claimed |
| US-5269815-A | Process for the fluorescent whitening of hydrophobic textile material with disperse fluorescent whitening agents from super-critical carbon dioxide | CIBA-GEIGY CORPORATION (US) | 1993-12-14 | — | — | US | claimed |
| EP-0543779-A1 | Process for optical bleaching of hydrophobic textile material with disperse optical brightness in supercritical CO2 | CIBA-GEIGY AG (CH) | 1993-05-26 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180305391-A1 | COFACTOR ANALOGS AS METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | NNMT, BHMT, MAT2B | RAB9A 2425/4885ALDH1A1 411/4885NPC1 2482/4885 |
| US-20160326161-A1 | SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS | SSB, TLR7, TLR8 | RAB9A 1739/4885ALDH1A1 4592/4885NPC1 3497/4885 |
| US-20210024489-A1 | TREATMENT AND PREVENTION OF NEUROPATHIC PAIN WITH P2Y14 ANTAGONISTS | P2RY14, P2RY4, P2RY13 | RAB9A 3104/4885ALDH1A1 2346/4885NPC1 2617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.