SCHEMBL5586614

SCHEMBL5586614

C=CCC(=O)O[Si](C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.34
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.31
PKM P14618 1/20 0.31
TSHR P16473 2/20 0.31
HPGD P15428 1/20 0.30
PRKCA P17252 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30954267 0.80 ALDH1A1 (0.35) ALDH1A1
SCHEMBL3482402 0.77 LMNA (0.42) ALDH1A1LMNATSHR
SCHEMBL31756031 0.76 ALDH1A1 (0.32) HTTALDH1A1GAAPRKCA
SCHEMBL1155508 0.76
SCHEMBL17736530 0.74 ALDH1A1 (0.53) ALDH1A1LMNATSHRHPGD
SCHEMBL22398867 0.73 MAPT (0.40) HTTALDH1A1GAAPKMTSHR
SCHEMBL20398198 0.73
SCHEMBL183554 0.72
SCHEMBL4644947 0.72
SCHEMBL6697776 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117801616-A High-dispersion polymer cement waterproof paint and preparation method thereof 科之杰新材料集团有限公司 2024-04-02 CN claimed
CN-117801448-A High-wetting quick-drying sealing material and preparation method thereof 科之杰新材料集团有限公司 2024-04-02 CN claimed
EP-3705535-B1 ORGANOPOLYSILOXANE COMPOSITION, AND ORGANIC SILICON COMPOUND AND PRODUCTION METHOD THEREFOR SHINETSU CHEMICAL CO (JP) 2025-06-04 EP disclosed
EP-3323505-B1 HYDROSILYLATION REACTION CATALYST UNIV KYUSHU NAT UNIV CORP (JP) 2024-07-17 EP disclosed
CN-117801448-A High-wetting quick-drying sealing material and preparation method thereof 科之杰新材料集团有限公司 2024-04-02 CN disclosed
CN-117801616-A High-dispersion polymer cement waterproof paint and preparation method thereof 科之杰新材料集团有限公司 2024-04-02 CN disclosed
US-11834556-B2 Organopolysiloxane composition, and organic silicon compound and production method therefor SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-05 US disclosed
CN-111278924-B Organopolysiloxane composition, organosilicon compound, and method for producing same 信越化学工业株式会社 2023-07-21 CN disclosed
EP-3280496-B1 EXTENDED LONGEVITY FRAGRANCE DELIVERY COMPOSITION MOMENTIVE PERFORMANCE MAT INC (US) 2022-07-20 EP disclosed
US-20220220260-A1 ORGANOPOLYSILOXANE COMPOSITION, AND ORGANIC SILICON COMPOUND AND PRODUCTION METHOD THEREFOR SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-07-14 US disclosed
EP-3406616-B1 NOVEL ISOCYANIDE COMPOUND AND HYDROSILYLATION REACTION CATALYST SHINETSU CHEMICAL CO (JP) 2022-06-29 EP disclosed
US-8455141-B2 Polymer electrolyte as well as polymer electrolyte membrane, membrane electrode assembly and polymer electrolyte fuel cell using the same TORAY INDUSTRIES, INC. (JP) 2013-06-04 US disclosed
US-20100210491-A1 Silicone Wax Emulsion and Method of Manufacture GENESEE POLYMERS CORPORATION 2010-08-19 US disclosed
CN-100446312-C Polymer electrolyte, polymer electrolyte membrane therefrom, membrane electrode assembly and polymer electrolyte fuel cell TORAY INDUSTRIES (JP) 2008-12-24 CN disclosed
US-20070134530-A1 Polymer electrolyte as well as polymer electrolyte membrane, membrane electrode assembly and polymer electrolyte fuel cell using the same TORAY INDUSTRIES, INC. (JP) 2007-06-14 US disclosed
CN-1788377-A Polymer electrolyte, polymer electrolyte membrane therefrom, membrane electrode assembly and polymer electrolyte fuel cell TORAY INDUSTRIES (JP) 2006-06-14 CN disclosed
EP-1641063-A1 POLYMER ELECTROLYTE, POLYMER ELECTROLYTE MEMBRANE THEREFROM, MEMBRANE ELECTRODE ASSEMBLY AND POLYMER ELECTROLYTE FUEL CELL TORAY INDUSTRIES, INC. (JP) 2006-03-29 EP disclosed
EP-0525782-B1 Process for the preparation of functionalised diphenylsiloxane-dimethylsiloxane copolymers DOW CORNING TORAY SILICONE (JP) 1996-09-04 EP disclosed
US-5223596-A DIPHENYSILOXANE-DIMETHYLSIOXANE COPOLYMER AND METHOD FOR THE PREPARATION THEREOF DOW CORNING TORAY SILICONE CO., LTD. (JP) 1993-06-29 US disclosed
EP-0525782-A1 Process for the preparation of functionalised diphenylsiloxane-dimethylsiloxane copolymers Dow Corning Toray Silicone Company, Limited (JP) 1993-02-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220220260-A1 ORGANOPOLYSILOXANE COMPOSITION, AND ORGANIC SILICON COMPOUND AND PRODUCTION METHOD THEREFOR SEM1, ILK, SI HTT 1775/4885ALDH1A1 1281/4885LMNA 1735/4885
US-20100210491-A1 Silicone Wax Emulsion and Method of Manufacture SOAT1, SOAT2, MSMO1 HTT 1991/4885ALDH1A1 2474/4885LMNA 814/4885
US-11834556-B2 Organopolysiloxane composition, and organic silicon compound and production method therefor SEM1, ILK, SI HTT 1775/4885ALDH1A1 1281/4885LMNA 1735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.