SCHEMBL5586908

SCHEMBL5586908

Oc1cccc(C(F)F)c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.52
ALDH1A1 P00352 5/20 0.52
LMNA P02545 4/20 0.52
ALOX15 P16050 4/20 0.52
HSD17B10 Q99714 4/20 0.52
CA2 P00918 3/20 0.52
RECQL P46063 3/20 0.52
TDP1 Q9NUW8 3/20 0.52
CA1 P00915 2/20 0.52
EGFR P00533 2/20 0.52
FYN P06241 2/20 0.52
MMP9 P14780 2/20 0.52
ADAMTS4 O75173 1/20 0.52
MMP2 P08253 1/20 0.52
MMP8 P22894 1/20 0.52
CA6 P23280 1/20 0.52
CDK2 P24941 1/20 0.52
MMP12 P39900 1/20 0.52
ADAMTS5 Q9UNA0 1/20 0.52
BCHE P06276 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5587913 0.81 HPGD (0.50) HPGDALDH1A1LMNAALOX15HSD17B10
SCHEMBL2645544 0.79 GABRA1 (0.56) HPGDALDH1A1LMNAALOX15HSD17B10
SCHEMBL23082197 0.78 LMNA (0.50) HPGDALDH1A1LMNAALOX15HSD17B10
SCHEMBL29826430 0.78 ADRA2A (0.52) HPGDALDH1A1LMNAALOX15HSD17B10
SCHEMBL27494451 0.78 LMNA (0.44) HPGDALDH1A1LMNAALOX15HSD17B10
SCHEMBL8582907 0.77 LMNA (0.55) HPGDALDH1A1LMNAALOX15HSD17B10
SCHEMBL30291381 0.76 POLB (0.39) HPGDALDH1A1LMNAALOX15HSD17B10
SCHEMBL2045707 0.76 ALDH1A1 (0.56) HPGDALDH1A1LMNAHSD17B10CA2
SCHEMBL16797149 0.76 KIF11 (0.42) HPGDALDH1A1LMNAALOX15HSD17B10
SCHEMBL23645287 0.76 POLB (0.39) HPGDALDH1A1LMNAALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US disclosed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP disclosed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US disclosed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 HPGD 2689/4885ALDH1A1 2181/4885LMNA 178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.