SCHEMBL5587647

SCHEMBL5587647

COOc1c(C)c(C)c(C)c(C(=O)O)c1O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMG3 Q9BT73 1/20 0.39
LDHA P00338 2/20 0.38
LDHB P07195 2/20 0.38
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35
HSD17B10 Q99714 1/20 0.35
CYP3A4 P08684 3/20 0.34
MEN1 O00255 2/20 0.34
MAPT P10636 2/20 0.34
KMT2A Q03164 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
IDO1 P14902 2/20 0.34
POLB P06746 1/20 0.34
HPGD P15428 1/20 0.34
GFER P55789 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
SLC37A4 O43826 1/20 0.34
APP P05067 1/20 0.33
BACE1 P56817 1/20 0.33
IMPDH2 P12268 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5586798 0.89 PSMG3 (0.43) PSMG3LDHALDHBKDM4EALDH1A1
SCHEMBL5590552 0.80 ALDH1A1 (0.36) PSMG3LDHALDHBALDH1A1KMT2A
SCHEMBL5590236 0.78 LDHA (0.33) PSMG3LDHALDHBALDH1A1APP
SCHEMBL5589191 0.75 ESR1 (0.36) PSMG3LDHALDHBALDH1A1PLA2G2A
SCHEMBL5587843 0.74 PLA2G2A (0.36) MEN1KMT2ATDP1PLA2G2ATSHR
SCHEMBL8830267 0.74 LDHA (0.48) PSMG3LDHALDHBKDM4EALDH1A1
SCHEMBL10404342 0.73 LDHA (0.52) PSMG3LDHALDHBKDM4EALDH1A1
SCHEMBL5589254 0.73 PLA2G2A (0.39) MEN1KMT2ATDP1PLA2G2ATSHR
SCHEMBL5586829 0.73 PLA2G2A (0.39) MEN1KMT2ATDP1PLA2G2ATSHR
SCHEMBL5588648 0.73 PLA2G2A (0.39) MEN1KMT2ATDP1PLA2G2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US disclosed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP disclosed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US disclosed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 PSMG3 2197/4885LDHA 320/4885LDHB 486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.