Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1840644 | 0.85 | CTSS (0.59) | CTSBCTSSCTSLMEN1KMT2A | |
| SCHEMBL1837974 | 0.82 | ALDH1A1 (0.54) | CTSBCTSSCTSLALDH1A1MAPK1 | |
| SCHEMBL6840056 | 0.80 | SPHK1 (0.44) | CTSBCTSLMEN1KMT2AALDH1A1 | |
| SCHEMBL11644833 | 0.79 | MEN1 (0.46) | MEN1KMT2AALDH1A1EPHX2PRCP | |
| SCHEMBL5592243 | 0.78 | CTSB (0.45) | CTSBCTSSCTSLALDH1A1 | |
| SCHEMBL13177736 | 0.78 | CTSL (0.54) | CTSBCTSSCTSLALDH1A1 | |
| SCHEMBL12661032 | 0.78 | CTSL (0.54) | CTSBCTSSCTSLALDH1A1 | |
| SCHEMBL16391370 | 0.78 | CTSS (0.52) | CTSBCTSSCTSLALDH1A1 | |
| SCHEMBL1840338 | 0.77 | CTSK (0.53) | CTSBCTSSCTSLKMT2ATDP1 | |
| SCHEMBL15461470 | 0.77 | CTSB (0.50) | CTSBCTSSCTSLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010079405-A2 | AN IMPROVED PROCESS FOR PREPARING 1-(PENTANOYLAMINO)CYCLOPENTANECARBOXYLIC ACID | ALEMBIC LIMITED (IN) | 2010-07-15 | — | — | WO | disclosed |
| US-20100113798-A1 | PROCESS FOR PREPARATION OF IRBESARTAN | ALEMBIC LIMITED (IN) | 2010-05-06 | — | — | US | disclosed |
| US-20100113798-A1 | PROCESS FOR PREPARATION OF IRBESARTAN | ALEMBIC LIMITED (IN) | 2010-05-06 | — | — | US | disclosed |
| US-7652147-B2 | Process for preparation of Irbesartan | ALEMBIC LIMITED (IN) | 2010-01-26 | — | — | US | disclosed |
| US-7652147-B2 | Process for preparation of Irbesartan | ALEMBIC LIMITED (IN) | 2010-01-26 | — | — | US | disclosed |
| WO-2007049293-A1 | AN IMPROVED PROCESS FOR PREPARATION OF IRBESARTAN | ALEMBIC LIMITED (IN) | 2007-05-03 | — | — | WO | disclosed |
| US-20070099973-A1 | Process for preparation of Irbesartan | ALEMBIC LIMITED (IN) | 2007-05-03 | — | — | US | disclosed |
| US-20070099973-A1 | Process for preparation of Irbesartan | ALEMBIC LIMITED (IN) | 2007-05-03 | — | — | US | disclosed |
| EP-0475898-A1 | Azacyclic compounds | CIBA-GEIGY AG (CH) | 1992-03-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099973-A1 | Process for preparation of Irbesartan | AGTR1, NPR1, REN | CTSB 1487/4885CTSS 1699/4885CTSL 1498/4885 |
| US-20100113798-A1 | PROCESS FOR PREPARATION OF IRBESARTAN | PAH, AGTR2, AGTR1 | CTSB 1034/4885CTSS 1454/4885CTSL 920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.