Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8296463 | 0.94 | CTSL (0.47) | DDB1CRBNALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7360632 | 0.93 | CTSL (0.49) | DDB1CRBNALDH1A1 | |
| SCHEMBL15114553 | 0.85 | ALDH1A1 (0.49) | DDB1CRBNALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL15106342 | 0.81 | ALDH1A1 (0.51) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL15125245 | 0.81 | DDB1 (0.45) | DDB1CRBNALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL27032980 | 0.80 | LMNA (0.47) | DDB1CRBNALDH1A1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30916058 | 0.80 | ALDH1A1 (0.50) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL5592243 | 0.79 | CTSB (0.45) | DDB1CRBNALDH1A1 | |
| SCHEMBL7411019 | 0.77 | CTSL (0.46) | DDB1CRBNTDP1 | |
| SCHEMBL28369674 | 0.77 | DDB1 (0.46) | DDB1CRBNALDH1A1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1134219-B1 | CYCLOALKYL-SUBSTITUTED AMINOMETHYLPYRROLIDINE DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2005-06-15 | — | — | EP | disclosed |
| US-6573260-B1 | Antibiotics | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-06-03 | — | — | US | disclosed |
| EP-1134219-A1 | CYCLOALKYL-SUBSTITUTED AMINOMETHYLPYRROLIDINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |