Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 4/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 5/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 2/20 | 0.38 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3169338 | 0.82 | NPC1 (0.51) | HPGDSLDHABAZ2BKDM1AP4HA1 | |
| SCHEMBL2767722 | 0.79 | HPGDS (0.74) | HPGDSLDHABAZ2BHSD17B1HSD17B2 | |
| SCHEMBL3175080 | 0.78 | SCN2A (0.43) | CYP4F2CYP4A11 | |
| SCHEMBL2551371 | 0.78 | LDHA (0.73) | HPGDSLDHABAZ2BP4HA1P4HTM | |
| SCHEMBL27859597 | 0.76 | HSD17B1 (0.39) | KDM1AHSD17B1HSD17B2FYNNPC1 | |
| SCHEMBL5593121 | 0.75 | LDHA (0.64) | HPGDSCYP4F2CYP4A11LDHAKDM1A | |
| SCHEMBL30336313 | 0.74 | P4HTM (0.64) | HPGDSLDHABAZ2BP4HA1P4HTM | |
| SCHEMBL3196986 | 0.74 | P4HTM (0.64) | HPGDSLDHABAZ2BP4HA1P4HTM | |
| SCHEMBL7392910 | 0.73 | HRH3 (0.56) | P4HTMNPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4254469 | 0.73 | OPRM1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025775-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |
| WO-2007025775-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |