Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.68 |
| ▸ | CTSG | P08311 | 1/20 | 0.68 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.68 |
| ▸ | CMA1 | P23946 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202779 | 0.89 | NPC1 (0.64) | PRSS1CTSGCTRB1CMA1GAA | |
| Betamipron SCHEMBL4498475 | 0.86 | PRSS1 (0.70) | PRSS1CTSGCTRB1CMA1GAA | |
| Betamipron SCHEMBL605899 | 0.86 | PRSS1 (0.70) | PRSS1CTSGCTRB1CMA1GAA | |
| SCHEMBL22982704 | 0.86 | MAPT (0.58) | PRSS1CTSGCTRB1CMA1GAA | |
| SCHEMBL3192014 | 0.85 | LMNA (0.77) | PRSS1CTSGCTRB1CMA1GAA | |
| SCHEMBL10523300 | 0.82 | NR4A2 (0.59) | GAASMN1; SMN2LMNAPOLBHDAC1 | |
| SCHEMBL11776576 | 0.82 | ALDH1A1 (0.55) | PRSS1CTSGCTRB1CMA1GAA | |
| SCHEMBL30662627 | 0.82 | SMN1; SMN2 (0.54) | PRSS1CTSGCTRB1CMA1GAA | |
| SCHEMBL11146458 | 0.82 | PRSS1 (0.66) | PRSS1CTSGCTRB1CMA1GAA | |
| SCHEMBL10708907 | 0.82 | PRSS1 (0.66) | PRSS1CTSGCTRB1CMA1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029021-A1 | 1,5-SUBSTITUTED TETRAZOLES AS THERAPEUTIC COMPOUNDS | THE UNIVERSITY OF EDINBURGH (GB) | 2007-03-15 | — | — | WO | disclosed |
| WO-2007029021-A1 | 1,5-SUBSTITUTED TETRAZOLES AS THERAPEUTIC COMPOUNDS | THE UNIVERSITY OF EDINBURGH (GB) | 2007-03-15 | — | — | WO | disclosed |