Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.34 |
| ▸ | WNT1 | P04628 | 3/20 | 0.34 |
| ▸ | GSK3B | P49841 | 3/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.34 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593180 | 0.93 | CTSL (0.45) | CTSLCTSSCTSKCTSBHDAC3 | |
| SCHEMBL5592632 | 0.92 | CTSL (0.45) | CTSLCTSSCTSKCTSBHDAC3 | |
| SCHEMBL5592732 | 0.92 | CTSL (0.45) | CTSLCTSSCTSKCTSBHDAC3 | |
| SCHEMBL5592852 | 0.90 | CTSL (0.43) | CTSLCTSSCTSKCTSBWNT1 | |
| SCHEMBL5592917 | 0.85 | CTSL (0.58) | CTSLCTSSCTSKCTSBGLS | |
| SCHEMBL5592899 | 0.82 | CHEK1 (0.38) | CTSLCTSSCTSKCTSBHDAC1 | |
| SCHEMBL5592735 | 0.82 | CTSS (0.49) | CTSLCTSSCTSKCTSB | |
| SCHEMBL5592638 | 0.81 | CTSL (0.57) | CTSLCTSSCTSKCTSBGLS | |
| SCHEMBL5592691 | 0.81 | CTSS (0.49) | CTSLCTSSCTSKCTSBHDAC1 | |
| Trifluoroacetic Acid SCHEMBL5592759 | 0.80 | CTSL (0.47) | CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025775-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | claimed |