Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593518 | 0.80 | REN (0.41) | MEN1KMT2AALDH1A1BCHENAAA | |
| SCHEMBL3564135 | 0.78 | REN (0.48) | KMT2AALDH1A1BCHENAAAREN | |
| SCHEMBL3565755 | 0.77 | REN (0.39) | BCHERENTSHR | |
| SCHEMBL3565758 | 0.77 | REN (0.39) | BCHERENTSHR | |
| SCHEMBL9819777 | 0.65 | METAP2 (0.56) | KMT2AALDH1A1BCHENAAAREN | |
| SCHEMBL9819783 | 0.65 | METAP2 (0.56) | KMT2AALDH1A1BCHENAAAREN | |
| SCHEMBL3261774 | 0.62 | NAAA (0.46) | MEN1KMT2ANAAAEPHX1EPHX2 | |
| SCHEMBL4970440 | 0.62 | CYP2C19 (0.36) | MEN1KMT2AALDH1A1TSHREPHX1 | |
| SCHEMBL4972273 | 0.61 | CYP2C19 (0.36) | MEN1KMT2AALDH1A1TSHREPHX1 | |
| SCHEMBL7719994 | 0.61 | ACHE (0.38) | TSHREPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117560-A2 | PIPERIDINE AND MORPHOLINE RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-10-18 | — | — | WO | disclosed |