Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.56 |
| ▸ | PPARG | P37231 | 7/20 | 0.56 |
| ▸ | PPARD | Q03181 | 7/20 | 0.56 |
| ▸ | PPARA | Q07869 | 7/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | FABP4 | P15090 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TLR2 | O60603 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL22186969 | 0.98 | GPR84 (0.60) | AKR1B1GPR84PPARGPPARDPPARA | |
| Glutarate SCHEMBL899114 | 0.93 | AKR1B1 (0.62) | AKR1B1GPR84PPARGPPARDPPARA | |
| Dodecanoate SCHEMBL28063305 | 0.91 | GPR84 (0.71) | AKR1B1GPR84PPARGPPARDPPARA | |
| Stearic Acid SCHEMBL28063302 | 0.91 | GPR84 (0.71) | AKR1B1GPR84PPARGPPARDPPARA | |
| Stearic Acid SCHEMBL22159918 | 0.91 | GPR84 (0.71) | AKR1B1GPR84PPARGPPARDPPARA | |
| Bicarbonate SCHEMBL28108460 | 0.88 | NAAA (0.48) | AKR1B1GPR84PPARGPPARDPPARA | |
| Bicarbonate SCHEMBL2059473 | 0.88 | NAAA (0.48) | AKR1B1GPR84PPARGPPARDPPARA | |
| Bicarbonate SCHEMBL10886257 | 0.88 | NAAA (0.48) | AKR1B1GPR84PPARGPPARDPPARA | |
| Bicarbonate SCHEMBL8663181 | 0.86 | NAAA (0.52) | GPR84PPARGPPARDPPARAHDAC11 | |
| Bicarbonate SCHEMBL786724 | 0.86 | NAAA (0.52) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116769295-B | Conductive PC (polycarbonate) for conductive carrier tape sheet and preparation method thereof | 浦江亿通塑胶电子有限公司 | 2024-02-23 | — | — | CN | claimed |
| CN-117186069-A | Bis-1, 2, 3-triazole-dialkylalcohol derivative, preparation method thereof and application thereof in nuclide extraction | 肯特催化材料股份有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-116769295-A | Conductive PC (polycarbonate) for conductive carrier tape sheet and preparation method thereof | 浦江亿通塑胶电子有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-116694074-A | graphene/PI composite material and preparation method thereof | 南京工业大学 | 2023-09-05 | — | — | CN | claimed |
| CN-116515192-A | Graphene grafted potassium hexatitanate whisker/polyethylene composite material and preparation method thereof | 南京工业大学 | 2023-08-01 | — | — | CN | claimed |
| CN-113788510-B | Device suitable for reservoir ferro-manganese is got rid of | 江西师范大学 | 2023-06-20 | — | — | CN | claimed |
| CN-113803003-B | Plugging method for nano-micron development shale pores | 中石化石油工程技术服务有限公司 | 2023-05-05 | — | — | CN | claimed |
| CN-115108801-A | High-strength cement-based composite material applied to airport pavement | 平邑中联水泥有限公司 | 2022-09-27 | — | — | CN | claimed |
| CN-113803003-A | Plugging method for nano-micron developed shale pores | 中石化石油工程技术服务有限公司 | 2021-12-17 | — | — | CN | claimed |
| CN-113788510-A | Device suitable for reservoir iron and manganese are got rid of | 江西师范大学 | 2021-12-14 | — | — | CN | claimed |
| CN-113736436-A | Water-based drilling fluid for plugging high-temperature reservoir of shale and preparation method thereof | 中石化石油工程技术服务有限公司 | 2021-12-03 | — | — | CN | claimed |
| CN-113279260-A | Multifunctional graphene composite fiber for back cushion and preparation method thereof | 深圳联达技术实业有限公司 | 2021-08-20 | — | — | CN | claimed |
| US-20240156995-A1 | MOLECULAR PROBES AND METHODS OF USE | UNIV CASE WESTERN RESERVE (US) | 2024-05-16 | — | — | US | disclosed |
| CN-117820794-A | Polyacrylamide/graphene oxide composite hydrogel as well as preparation method and application thereof | 中国石油天然气集团有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-114314576-B | Graphene oxide carboxyl functional modification method | 西安近代化学研究所 | 2024-03-29 | — | — | CN | disclosed |
| CN-116769295-B | Conductive PC (polycarbonate) for conductive carrier tape sheet and preparation method thereof | 浦江亿通塑胶电子有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-211478143-U | Composite filtering membrane of biosensor | 上海硕创生物医药科技有限公司 | 2020-09-11 | — | — | CN | disclosed |
| CN-110702764-A | Composite filtering membrane of biosensor and preparation method thereof | 上海硕创生物医药科技有限公司 | 2020-01-17 | — | — | CN | disclosed |
| US-20180110886-A1 | MOLECULAR PROBES AND METHODS OF USE | CASE WESTERN RESERVE UNIVERSITY | 2018-04-26 | — | — | US | disclosed |
| JP-2007217194-A | METHOD FOR PRODUCING SURFACE-MODIFIED CARBON NANO-MATERIAL AND PT-BASED CATALYST | JAPAN ADVANCED INSTITUTE OF SCIENCE & TECHNOLOGY HOKURIKU | 2007-08-30 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240156995-A1 | MOLECULAR PROBES AND METHODS OF USE | EDNRB, FGB, FN1 | AKR1B1 3888/4885GPR84 2780/4885PPARG 2854/4885 |
| US-20180110886-A1 | MOLECULAR PROBES AND METHODS OF USE | EDNRB, FGB, FN1 | AKR1B1 3888/4885GPR84 2780/4885PPARG 2854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.