Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 4/20 | 0.41 |
| ▸ | ATP4B | P51164 | 4/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | ILK | Q13418 | 5/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4949209 | 0.94 | ATP4A (0.45) | ATP4AATP4BHTR1AHTR2AHTR7 | |
| SCHEMBL5597097 | 0.80 | PTGS1 (0.40) | ILKAPPKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL4949279 | 0.80 | MGLL (0.43) | KDM4EALDH1A1POLBSMN1; SMN2RAB9A | |
| SCHEMBL5596344 | 0.77 | RAB9A (0.46) | ILKKDM4EALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL5596467 | 0.76 | NPC1 (0.48) | ILKKDM4EALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL5596406 | 0.73 | ILK (0.51) | ILKAPPKDM4EALDH1A1POLB | |
| SCHEMBL5596393 | 0.72 | KDM4E (0.36) | ILKAPPKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4948593 | 0.70 | MAPK8 (0.55) | ILKALDH1A1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL4946974 | 0.68 | ALDH1A1 (0.40) | ATP4AATP4BHTR1AHTR2AHTR7 | |
| SCHEMBL1982607 | 0.68 | KDM4E (0.51) | ILKAPPKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812072-B1 | BENZOTHIAZOLE FORMULATIONS AND USE THEREOF | ARES TRADING SA (CH) | 2008-10-22 | — | — | EP | disclosed |