Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5599937 | 0.78 | CHRNB2 (0.35) | L3MBTL1CHRNB2CHRNA4PDE4B | |
| SCHEMBL5599046 | 0.73 | TDP1 (0.39) | KMT2AMAPTPTGESALOX5PPARG | |
| SCHEMBL5601356 | 0.72 | CHRNB2 (0.39) | CHRNB2CHRNA4PDE4DKMT2AMAPT | |
| SCHEMBL5599549 | 0.68 | L3MBTL1 (0.42) | L3MBTL1CHRNB2CHRNA4KMT2AMAPT | |
| SCHEMBL5599192 | 0.67 | LMNA (0.36) | L3MBTL1CHRNB2CHRNA4KMT2AMAPT | |
| SCHEMBL4060494 | 0.67 | KDM4E (0.44) | L3MBTL1CHRNB2CHRNA4KMT2AMAPT | |
| SCHEMBL9254321 | 0.65 | CALM1 (0.47) | CALM1 | |
| SCHEMBL5615878 | 0.63 | L3MBTL1 (0.38) | L3MBTL1KMT2AMAPTKDM4EFFAR1 | |
| SCHEMBL19582677 | 0.63 | L3MBTL1 (0.40) | L3MBTL1CHRNB2CHRNA4KMT2AMAPT | |
| SCHEMBL9250450 | 0.63 | SMPD1 (0.43) | CALM1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1746986-A1 | ACTIVE SUBSTANCE COMBINATION COMPRISING A CARBINOL COMBINED TO AT LEAST AN NSAID | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-01-31 | — | — | EP | claimed |
| WO-2005097099-A1 | ACTIVE SUBSTANCE COMBINATION COMPRISING A CARBINOL COMBINED TO AT LEAST AN NSAID | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2005-10-20 | — | — | WO | claimed |