Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 7/20 | 0.46 |
| ▸ | MEP1A | Q16819 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5548483 | 0.87 | LOXL2 (0.52) | MEP1BFOLH1MRGPRX4SMN1; SMN2RAB9A | |
| SCHEMBL27523354 | 0.87 | FOLH1 (0.47) | MEP1BFOLH1MRGPRX4NR1H4TP53 | |
| SCHEMBL11503179 | 0.84 | CYP1A2 (0.45) | NR1H4NFKB1 | |
| SCHEMBL5603701 | 0.83 | ALDH1A1 (0.43) | MEP1BNR1H4SMN1; SMN2RAB9A | |
| SCHEMBL7662463 | 0.82 | S1PR1 (0.39) | — | |
| SCHEMBL7763429 | 0.81 | MEN1 (0.41) | RAB9A | |
| SCHEMBL5663890 | 0.79 | LOXL2 (0.38) | MRGPRX4NFKB1SMN1; SMN2 | |
| SCHEMBL4518626 | 0.79 | HSD11B1 (0.38) | MRGPRX4TP53 | |
| SCHEMBL6500462 | 0.79 | GPR35 (0.47) | NR1H4SMN1; SMN2RAB9A | |
| SCHEMBL3865771 | 0.78 | ENPP2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007066099-A1 | PYRIMIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2007-06-14 | — | — | WO | disclosed |
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |