Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 12/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5663890 | 0.85 | LOXL2 (0.38) | RIPK1ENPP2 | |
| SCHEMBL11503179 | 0.85 | CYP1A2 (0.45) | RIPK1 | |
| SCHEMBL4518626 | 0.82 | HSD11B1 (0.38) | MAOBRIPK1 | |
| SCHEMBL5604152 | 0.82 | MEP1B (0.46) | — | |
| SCHEMBL3865771 | 0.82 | ENPP2 (0.44) | RIPK1ENPP2 | |
| SCHEMBL7763429 | 0.81 | MEN1 (0.41) | RIPK1 | |
| SCHEMBL5548483 | 0.80 | LOXL2 (0.52) | — | |
| SCHEMBL4517778 | 0.78 | CYP1A2 (0.51) | MAOB | |
| SCHEMBL6500462 | 0.77 | GPR35 (0.47) | MAOBPDK1PDK2PDK3PDK4 | |
| SCHEMBL6487700 | 0.76 | BCHE (0.38) | MAOBPDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348478-B1 | BLOOD COAGULATION FACTORS AND ANTICOAGULANTS | TEIJIN LIMITED (JP) | 2002-02-19 | — | — | US | disclosed |
| EP-1043311-A1 | BIPHENYLAMIDINE DERIVATIVES | TEIJIN LIMITED (JP) | 2000-10-11 | — | — | EP | disclosed |