SCHEMBL5606468

SCHEMBL5606468

COC(=Cc1ccc(O)cc1)C(=O)OC(C)(C)C

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 10/20 0.54
MIF P14174 2/20 0.50
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA12 O43570 1/20 0.44
TYR P14679 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 2/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5606467 1.00 ABCG2 (0.54) ABCG2MIFCA1CA2CA12
SCHEMBL2409609 0.85 ABCG2 (0.47) ABCG2CA1CA2ALDH1A1MEN1
SCHEMBL5606965 0.84 ABCG2 (0.61) ABCG2MIFCA1CA2CA12
SCHEMBL5606962 0.84 ABCG2 (0.61) ABCG2MIFCA1CA2CA12
SCHEMBL5606934 0.83 CA12 (0.48) ABCG2MIFCA1CA2CA12
SCHEMBL5606938 0.83 CA12 (0.48) ABCG2MIFCA1CA2CA12
SCHEMBL5607374 0.81 ALDH1A1 (0.45) ABCG2MIFCA1CA2CA12
SCHEMBL5607378 0.81 ALDH1A1 (0.45) ABCG2MIFCA1CA2CA12
SCHEMBL5606469 0.80 ALDH1A1 (0.50) ABCG2MIFCA1CA2CA12
SCHEMBL11042783 0.80 ABCG2 (0.56) ABCG2MIFCA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070142472-A1 Process for producing optically active 3-(4-hydroxyphenyl)proprionic acids TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-06-21 US disclosed
EP-1687250-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-(4-HYDROXYPHENYL)PROPIONIC ACIDS Takasago International Corporation (JP) 2006-08-09 EP disclosed
WO-2005051882-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-(4-HYDROXYPHENYL)PROPIONIC ACIDS TAKASAGO INTERNATIONAL CORPORATION (JP) 2005-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070142472-A1 Process for producing optically active 3-(4-hydroxyphenyl)proprionic acids ALDH1A2, ALDH1A3, GRHPR ABCG2 3631/4885MIF 2713/4885CA1 329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.