Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597963 | 0.72 | CCKBR (0.62) | CCKBRALDH1A1MCL1HSD17B10CYP2C9 | |
| SCHEMBL5606256 | 0.69 | TSHR (0.47) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL72502 | 0.65 | HDAC3 (0.65) | KDM4EHDAC2HDAC3HDAC4HDAC1 | |
| SCHEMBL6180052 | 0.65 | METAP2 (0.41) | ALDH1A1POLB | |
| SCHEMBL1034849 | 0.64 | CA2 (0.51) | KDM4EHDAC2HDAC3HDAC4HDAC1 | |
| SCHEMBL2703947 | 0.64 | CYP2A6 (0.47) | CCKBRKDM4EHDAC2HDAC3HDAC4 | |
| SCHEMBL31287752 | 0.64 | CA2 (0.51) | KDM4EHDAC2HDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL4254555 | 0.64 | HDAC3 (0.62) | KDM4EHDAC2HDAC3HDAC4HDAC1 | |
| Bicarbonate SCHEMBL9262624 | 0.64 | HDAC2 (0.49) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7112980 | 0.64 | ALOX5 (0.40) | CCKBRHDAC2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1815860-A2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2007-08-08 | — | — | EP | disclosed |
| EP-1465638-A2 | PHOSPHATE TRANSPORT INHIBITORS | GENZYME CORPORATION (US) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003057225-A2 | PHOSPHATE TRANSPORT INHIBITORS | GENZYME CORPORATION (US) | 2003-07-17 | — | — | WO | disclosed |