SCHEMBL5606539

SCHEMBL5606539

CC1Cc2c(OCBr)ccc(OCBr)c2C1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 3/20 0.36
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3657142 0.70 HTR1A (0.42) ADRA1A
SCHEMBL2417663 0.69 HTR1A (0.44) ADRA1A
SCHEMBL3656477 0.65
SCHEMBL18018511 0.64 ADRA1A (0.52) ADRA1AACHE
SCHEMBL7156116 0.61 ACHE (0.40) ACHE
SCHEMBL31319551 0.61 KDM4E (0.46)
SCHEMBL11075914 0.59 RXRA (0.52)
SCHEMBL5607629 0.59 RXRB (0.52)
SCHEMBL11836462 0.58 TDP1 (0.60)
SCHEMBL11198349 0.58 CA12 (0.62)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1833859-A2 HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION ExxonMobil Chemical Patents Inc. (US) 2007-09-19 EP disclosed
WO-2006065843-A2 HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed
WO-2006065809-A2 HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed