Water

Water

SCHEMBL561304

O.O.[Y]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL10534404 1.00
Water SCHEMBL8943522 1.00
Water SCHEMBL28274731 1.00
Water SCHEMBL40570 1.00
Water SCHEMBL79565 1.00
Water SCHEMBL21816890 1.00
Water SCHEMBL333899 1.00
Water SCHEMBL10795519 1.00
Water SCHEMBL9418317 1.00
Water SCHEMBL25260041 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118612964-A Aluminum-based composite material substrate with insulating layer and circuit layer and manufacturing method 西安广杰半导体有限公司 2024-09-06 CN claimed
CN-118407105-A Wide-temperature-range ternary system solid self-lubricating coating, and preparation method and application thereof 中国农业机械化科学研究院集团有限公司 2024-07-30 CN claimed
CN-116925518-A Polyaryletherketone polymer alloy raw material and preparation method thereof 中国航空制造技术研究院 2023-10-24 CN claimed
US-11717811-B2 Macroporous oxygen carrier solid with an oxide ceramic matrix, method for the preparation thereof, and use thereof for a chemical-looping oxidation-reduction method IFP Energies Nouvelles (FR) 2023-08-08 US claimed
US-11628426-B2 Catalyst for chemical looping combustion UTI LIMITED PARTNERSHIP (CA) 2023-04-18 US claimed
EP-4031628-A1 PAINT COMPOSITIONS COMPRISING ZIRCONIUM DIOXIDE PIGMENT PARTICLES ImerTech SAS (FR) 2022-07-27 EP claimed
CN-216915141-U Scratch-resistant and wear-resistant LOW-E laminated glass 东莞市银建玻璃工程有限公司 2022-07-08 CN claimed
CN-114423832-A Coating compositions comprising zirconium dioxide pigment particles 伊梅斯切公司 2022-04-29 CN claimed
US-20210339231-A1 CATALYST FOR CHEMICAL LOOPING COMBUSTION UTI LIMITED PARTNERSHIP (CA) 2021-11-04 US claimed
CN-212958885-U Engine piston 江苏王牌动力科技有限公司 2021-04-13 CN claimed
CN-1099702-C Method of manufacturing semiconductor device NEC CORP (JP) 2003-01-22 CN claimed
EP-1064238-B1 COMPOSITION, MANUFACTURING, AND USE OF SILICON NITRIDE AS A BIOMATERIAL FOR MEDICAL PURPOSE BIOMAT SYSTEM AB (SE) 2002-12-18 EP claimed
CN-1301241-A Composition, manufacturing, and use of silicon nitride as a biomaterial for medical purpose BIOMAT SYSTEM HB (SE) 2001-06-27 CN claimed
EP-1064238-A1 COMPOSITION, MANUFACTURING, AND USE OF SILICON NITRIDE AS A BIOMATERIAL FOR MEDICAL PURPOSE Biomat System AB (SE) 2001-01-03 EP claimed
WO-1999047471-A1 COMPOSITION, MANUFACTURING, AND USE OF SILICON NITRIDE AS A BIOMATERIAL FOR MEDICAL PURPOSE BIOMAT SYSTEM AB (SE) 1999-09-23 WO claimed
CN-1211816-A Method of manufacturing semiconductor device NEC CORP (JP) 1999-03-24 CN claimed
EP-0096773-B1 METHOD OF MAKING HIGH DIELECTRIC CONSTANT INSULATORS AND CAPACITORS USING SAME International Business Machines Corporation (US) 1987-03-25 EP claimed
US-4432035-A OXIDATION OF TRANSITION METAL-SILICON ALLOY INTERNATIONAL BUSINESS MACHINES CORP. (US) 1984-02-14 US claimed
EP-0096773-A2 Method of making high dielectric constant insulators and capacitors using same International Business Machines Corporation (US) 1983-12-28 EP claimed
US-3963597-A Electrically regenerative oxygen trap AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) 1976-06-15 US claimed