SCHEMBL561422

SCHEMBL561422

O=C1OC(=O)C2=C1[C@@H]1CC[C@H]2C1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL346876 1.00 TSHR (0.32) TSHR
SCHEMBL10759055 1.00 TSHR (0.32) TSHR
SCHEMBL18022413 0.84 — —
SCHEMBL2647824 0.81 TSHR (0.31) TSHR
SCHEMBL304318 0.78 CEL (0.33) TSHR
SCHEMBL16192652 0.78 — —
SCHEMBL16192412 0.78 ALDH1A1 (0.31) TSHR
SCHEMBL6238652 0.76 KMT2A (0.36) —
SCHEMBL16192558 0.75 TRPA1 (0.38) —
SCHEMBL16192185 0.74 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10442894-B2 Microporous polyimide sponge and method for producing the same INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2019-10-15 — — US claimed
US-20190127547-A1 NANOPOROUS MICRO-SPHERICAL POLYIMIDE AEROGELS AND METHOD FOR PREPARING SAME Han, Haksoo (KR) 2019-05-02 — — US claimed
US-20170298185-A1 MICROPOROUS POLYIMIDE SPONGE AND METHOD FOR PRODUCING THE SAME INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2017-10-19 — — US claimed
US-20160102184-A1 MICROPOROUS POLYIMIDE SPONGE AND METHOD FOR PRODUCING THE SAME INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2016-04-14 — — US claimed
US-20080160317-A1 Optoelectronic device GELCORE LLC 2008-07-03 — — US claimed
US-20080001140-A1 Optoelectronic device GELCORE LLC 2008-01-03 — — US claimed
US-20070295956-A1 Optoelectronic device GELCORE LLC 2007-12-27 — — US claimed
US-20050113536-A1 Epoxy polymer precursors and epoxy polymers resistant to damage by high-energy radiation ARMSTRONG SEAN E (US) 2005-05-26 — — US claimed
US-20050107580-A1 Epoxy polymer precursors and epoxy polymers resistant to damage by high-energy radiation ARMSTRONG SEAN E (US) 2005-05-19 — — US claimed
US-20030236388-A1 Epoxy polymer precursors and epoxy polymers resistant to damage by high-energy radiation GENERAL ELECTRIC COMPANY 2003-12-25 — — US claimed
US-20230416468-A1 BIOACTIVE POLYETHYLENE COPOLYMER, POLYETHYLENE MACROMOLECULE AND RELATED METHODS THEREOF MITSUI CHEMICALS, INC. (JP) 2023-12-28 — — US disclosed
US-20230399457-A1 Bioactive Synthetic Copolymer, Bioactive Macromolecule and Related Methods Thereof AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2023-12-14 — — US disclosed
EP-4237465-A1 BIOACTIVE POLYETHYLENE COPOLYMER, POLYETHYLENE MACROMOLECULE AND RELATED METHODS THEREOF Agency for Science, Technology and Research (SG) 2023-09-06 — — EP disclosed
CN-116648471-A Bioactive polyethylene copolymers, polyethylene macromolecules and related methods 新加坡科技研究局 2023-08-25 — — CN disclosed
CN-116648472-A Bioactive synthetic copolymers, bioactive macromolecules and related methods 新加坡科技研究局 2023-08-25 — — CN disclosed
US-20050043353-A1 Cinchona-alkaloid-based catalysts, and asymmetric alcoholysis of cyclic anhydrides using them BRANDEIS UNIVERSITY 2005-02-24 — — US disclosed
US-20030236388-A1 Epoxy polymer precursors and epoxy polymers resistant to damage by high-energy radiation GENERAL ELECTRIC COMPANY 2003-12-25 — — US disclosed
US-6309719-B1 CONTAINING NORBORNANEDICARBOXYLIC ACID ARTEVA NORTH AMERICA S.A.R.L. (CH) 2001-10-30 — — US disclosed
US-6187435-B1 FOR REINFORCEMENT OF PLASTICS, CEMENTS; IN TEXTILES FOR WARPS; TENSILE STRENGTH, WEAR RESISTANCE VERTROTEX FRANCE (FR) 2001-02-13 — — US disclosed
US-5807969-A Preparation of poly-O-hydroxyamides and poly O-mercaptoamides SIEMENS AKTIENGESELLSCHAFT (DE) 1998-09-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230416468-A1 BIOACTIVE POLYETHYLENE COPOLYMER, POLYETHYLENE MACROMOLECULE AND RELATED METHODS THEREOF FGF1, FGF2, HDGF TSHR 3866/4885
US-20050043353-A1 Cinchona-alkaloid-based catalysts, and asymmetric alcoholysis of cyclic anhydrides using them CA7, CA9, CA1 TSHR 3732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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