Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6911396 | 0.80 | TSHR (0.48) | TSHRALDH1A1AOC3TAAR1TP53 | |
| SCHEMBL6904854 | 0.80 | TSHR (0.48) | TSHRALDH1A1AOC3TAAR1TP53 | |
| SCHEMBL6913522 | 0.76 | TP53 (0.44) | TSHRALDH1A1AOC3TAAR1TP53 | |
| SCHEMBL6913267 | 0.73 | SIGMAR1 (0.42) | TSHRALDH1A1AOC3TAAR1TP53 | |
| SCHEMBL6904976 | 0.70 | KCNH2 (0.42) | TP53SIGMAR1SLC6A2SLC6A4ADRA1A | |
| SCHEMBL272369 | 0.69 | CALM1 (0.50) | TSHRALDH1A1TAAR1TP53CALM1 | |
| SCHEMBL28833326 | 0.67 | CALM1 (0.47) | TSHRALDH1A1TAAR1TP53CALM1 | |
| Water SCHEMBL9141797 | 0.67 | CALM1 (0.47) | TSHRALDH1A1TAAR1TP53CALM1 | |
| SCHEMBL6915634 | 0.67 | TSHR (0.47) | TSHRALDH1A1AOC3TAAR1TP53 | |
| SCHEMBL6905115 | 0.67 | TP53 (0.44) | TSHRALDH1A1AOC3TAAR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3288953-B1 | BIS(AMINOPHENYLPHENOL) LIGANDS AND TRANSITION METAL COMPOUNDS PREPARED THEREFROM | UNIVATION TECH LLC (US) | 2021-01-06 | — | — | EP | disclosed |
| US-10696641-B2 | Bis(aminophenylphenol) ligands and transition metal catalysts prepared therefrom | UNIVATION TECHNOLOGIES, LLC (US) | 2020-06-30 | — | — | US | disclosed |
| US-10689314-B2 | Methods for preparing bridged bi-aromatic ligands | UNIVATION TECHNOLOGIES, LLC (US) | 2020-06-23 | — | — | US | disclosed |
| US-10654029-B2 | Bridged bi-aromatic ligands and olefin polymerization catalysts prepared therefrom | UNIVATION TECHNOLOGIES, LLC (US) | 2020-05-19 | — | — | US | disclosed |
| EP-3632920-A1 | METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS | Univation Technologies, LLC (US) | 2020-04-08 | — | — | EP | disclosed |
| EP-3286162-B1 | METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS | UNIVATION TECH LLC (US) | 2019-10-23 | — | — | EP | disclosed |
| EP-3285923-B1 | BRIDGED BI-AROMATIC LIGANDS AND OLEFIN POLYMERIZATION CATALYSTS PREPARED THEREFROM | UNIVATION TECH LLC (US) | 2019-07-17 | — | — | EP | disclosed |
| US-20190111414-A1 | BRIDGED BI-AROMATIC LIGANDS AND OLEFIN POLYMERIZATION CATALYSTS PREPARED THEREFROM | UNIVATION TECHNOLOGIES, LLC (US) | 2019-04-18 | — | — | US | disclosed |
| US-10252967-B2 | Bridged bi-aromatic ligands and transition metal compounds prepared therefrom | UNIVATION TECHNOLOGIES, LLC (US) | 2019-04-09 | — | — | US | disclosed |
| US-10239809-B2 | Methods for preparing bridged bi-aromatic ligands | UNIVATION TECHNOLOGIES, LLC (US) | 2019-03-26 | — | — | US | disclosed |
| WO-2003051936-A1 | BIDENTATE LIGAND BASED CATALYST FOR THE POLYMERIZATION OF OLEFINS | UNIVATION TECHNOLOGIES, LLC (US) | 2003-06-26 | — | — | WO | disclosed |
| EP-0993464-B1 | CATALYST FOR THE PRODUCTION OF OLEFIN POLYMERS | UNION CARBIDE CHEM PLASTIC (US) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002090366-A1 | OLEFIN POLYMERIZATION CATALYSTS CONTAINING A PYRROLE BISIMINE LIGAND | UNIVATION TECHNOLOGIES, LLC (US) | 2002-11-14 | — | — | WO | disclosed |
| WO-2002053603-A2 | POLYMERIZATION CATALYST SYSTEM, POLYMERIZATION PROCESS AND POLYMER THEREFROM | UNIVATION TECHNOLOGIES, LLC (US) | 2002-07-11 | — | — | WO | disclosed |
| US-20020086960-A1 | Polymerization catalyst system, polymerization process and polymer therefrom | UNIVATION TECHNOLOGIES, LLC | 2002-07-04 | — | — | US | disclosed |
| US-20020065379-A1 | Catalyst for the production of olefin polymers | MURRAY REX EUGENE (US) | 2002-05-30 | — | — | US | disclosed |
| US-6352953-B1 | TRANSITION METAL COMPLEX HAVING 5-MEMBERED RING FORMED BY TRANSITION METAL COMPOUND OF GROUP IVB, TWO CARBONS, METAL OF GROUP IIIA AND HYDROGEN | JAPAN POLYOLEFINS CO., LTD. (JP) | 2002-03-05 | — | — | US | disclosed |
| US-6150544-A | Transition metal compound and catalyst containing the same for polymerization of olefins | JAPAN POLYOLEFINS CO., LTD. (JP) | 2000-11-21 | — | — | US | disclosed |
| US-6103657-A | Catalyst for the production of olefin polymers | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2000-08-15 | — | — | US | disclosed |
| US-6096676-A | METALLOCENE COORDINATION CATALYSTS BASED ON A GROUP IVB METAL AND AN ACTIVATING COCATALYST; ADDITION POLYMERATION OF OLEFINS, ALPHA-OLEFINS AND DIENES; HOMOGENEITY; KINETICS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2000-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10696641-B2 | Bis(aminophenylphenol) ligands and transition metal catalysts prepared therefrom | WASF2, WEE2, THEM6 | TSHR 3246/4885ALDH1A1 2023/4885AOC3 2835/4885 |
| US-10689314-B2 | Methods for preparing bridged bi-aromatic ligands | TYR, AOC2, BICRA | TSHR 3980/4885ALDH1A1 1187/4885AOC3 4/4885 |
| US-10654029-B2 | Bridged bi-aromatic ligands and olefin polymerization catalysts prepared therefrom | WASF2, WEE2, PICALM | TSHR 4569/4885ALDH1A1 1801/4885AOC3 220/4885 |
| US-10239809-B2 | Methods for preparing bridged bi-aromatic ligands | AOC1, TYR, DDT | TSHR 4401/4885ALDH1A1 1481/4885AOC3 4/4885 |
| US-20190111414-A1 | BRIDGED BI-AROMATIC LIGANDS AND OLEFIN POLYMERIZATION CATALYSTS PREPARED THEREFROM | WASF2, WEE2, PICALM | TSHR 4569/4885ALDH1A1 1801/4885AOC3 220/4885 |
| US-10252967-B2 | Bridged bi-aromatic ligands and transition metal compounds prepared therefrom | WEE2, WEE1, AHR | TSHR 2885/4885ALDH1A1 1250/4885AOC3 1433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.