Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | HNF4A | P41235 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 3/20 | 0.31 |
| ▸ | EDNRA | P25101 | 3/20 | 0.31 |
| ▸ | FABP3 | P05413 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL217236 | 0.79 | PARP10 (0.35) | HTR1AHTR7DRD2CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL217523 | 0.79 | HTR1A (0.36) | HTR1AHTR7DRD2CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL5616595 | 0.79 | ADRA2C (0.33) | CYP11B2CYP17A1CYP19A1CYP11B1ADRA2C | |
| Hydrochloric Acid SCHEMBL1775471 | 0.78 | PDCD1 (0.31) | CHRNB2CHRNA4PDCD1CD274HNF4A | |
| Hydrochloric Acid SCHEMBL5616347 | 0.78 | PDCD1 (0.34) | HTR1AHTR7CHRNB2CHRNA4BRD4 | |
| SCHEMBL3672615 | 0.78 | HTR1A (0.35) | HTR1AHTR7DRD2CHRNB2CHRNA4 | |
| SCHEMBL5345743 | 0.77 | HTR1A (0.34) | HTR1AHTR7DRD2CHRNB2CHRNA4 | |
| SCHEMBL7599331 | 0.77 | HTR1A (0.34) | HTR1AHTR7DRD2CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL6248017 | 0.75 | FAAH (0.32) | HTR2B | |
| SCHEMBL5354721 | 0.72 | HTR1A (0.33) | HTR1AHTR7DRD2CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007023618-A1 | HOMOPOLYMER AND COPOLYMER, AND PRODUCTION PROCESS THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-03-01 | — | — | WO | disclosed |