Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.69 |
| ▸ | MMP3 | P08254 | 2/20 | 0.69 |
| ▸ | MMP9 | P14780 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 6/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | THRB | P10828 | 3/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.64 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.62 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.62 |
| ▸ | POLH | Q9Y253 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | SLCO2B1 | O94956 | 4/20 | 0.62 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.62 |
| ▸ | TP53 | P04637 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Robustaflavone SCHEMBL561807 | 0.94 | APP (0.77) | APPMMP3MMP9KMT2AMEN1 | |
| Robustaflavone SCHEMBL7643511 | 0.93 | APP (0.76) | APPMMP3MMP9KMT2AMEN1 | |
| Robustaflavone SCHEMBL7638211 | 0.93 | APP (0.76) | APPMMP3MMP9KMT2AMEN1 | |
| SCHEMBL17166016 | 0.87 | APP (0.70) | APPMMP3MMP9KMT2AMEN1 | |
| Robustaflavone SCHEMBL7454193 | 0.85 | KMT2A (0.66) | APPMMP3MMP9KMT2AMEN1 | |
| Robustaflavone SCHEMBL7517639 | 0.84 | APP (0.67) | APPMMP3MMP9KMT2AMEN1 | |
| Sumaflavone SCHEMBL30152146 | 0.82 | KMT2A (0.74) | APPMMP3MMP9KMT2AMEN1 | |
| Sumaflavone SCHEMBL13980979 | 0.82 | KMT2A (0.74) | APPMMP3MMP9KMT2AMEN1 | |
| Amentoflavone SCHEMBL312563 | 0.82 | MEN1 (0.80) | APPMMP3MMP9KMT2AMEN1 | |
| Amentoflavone SCHEMBL29929632 | 0.82 | MEN1 (0.80) | APPMMP3MMP9KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603225-A2 | ELECTRONICALLY MODIFIED REACTION INTERMIDEATES | Markou, Demetrios (US) | 2013-06-19 | — | — | EP | claimed |
| WO-2012024196-A2 | A NOVEL METHOD FOR CREATING, SUSPENDING AND STABILIZING ELECTRONICALLY MODIFIED REACTION INTERMIDEATES | MARKOU DEMETRIOS (US) | 2012-02-23 | — | — | WO | claimed |
| US-20120039796-A1 | Novel method for creating, suspending and stabilizing electronically modified oxygen derivatives, along with creating, suspending and stabilizing electronically modified reaction intermediates, in a bio compatible fluorocarbon suspension, for the purpose of inducing a cascading immune response in mammalian patients | MARKOU DEMETRIOS (US) | 2012-02-16 | — | — | US | claimed |
| EP-0833631-B1 | ROBUSTAFLAVONE AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS | ADVANCED LIFE SCIENCES INC (US) | 2002-11-13 | — | — | EP | claimed |
| US-20020068757-A1 | Biflavanoids and derivatives thereof as antiviral agents | ADVANCED LIFE SCIENCES, INC. | 2002-06-06 | — | — | US | claimed |
| US-6399654-B1 | ADMINISTERING MIXTURE OF VIRICIDE AND BIOFLAVANOID | ADVANCED LIFE SCIENCES, INC. | 2002-06-04 | — | — | US | claimed |
| WO-1998046238-A1 | BIFLAVINOIDS AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS, ALONE OR IN COMBINATION WITH AT LEAST ONE KNOWN ANTIVIRAL AGENT | MEDICHEM RESEARCH, INC. (US) | 1998-10-22 | — | — | WO | claimed |
| US-5773462-A | INFLUENZA THERAPY | MEDICHEM RESEARCH, INC. (US) | 1998-06-30 | — | — | US | claimed |
| EP-0833631-A1 | BIFLAVANOIDS AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS | MEDICHEM RESEARCH, INC. (US) | 1998-04-08 | — | — | EP | claimed |
| WO-1997000679-A1 | BIFLAVANOIDS AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS | MEDICHEM RESEARCH, INC. (US) | 1997-01-09 | — | — | WO | claimed |
| EP-1245230-A3 | Amentoflavone as an antiviral agent | Advanced Life Sciences Inc. (US) | 2003-11-26 | — | — | EP | disclosed |
| EP-0833631-B1 | ROBUSTAFLAVONE AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS | ADVANCED LIFE SCIENCES INC (US) | 2002-11-13 | — | — | EP | disclosed |
| EP-0833631-B1 | ROBUSTAFLAVONE AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS | ADVANCED LIFE SCIENCES INC (US) | 2002-11-13 | — | — | EP | disclosed |
| EP-1245230-A2 | Amentoflavone as an antiviral agent | Advanced Life Sciences Inc. (US) | 2002-10-02 | — | — | EP | disclosed |
| EP-1245230-A2 | Amentoflavone as an antiviral agent | Advanced Life Sciences Inc. (US) | 2002-10-02 | — | — | EP | disclosed |
| US-5773462-A | INFLUENZA THERAPY | MEDICHEM RESEARCH, INC. (US) | 1998-06-30 | — | — | US | disclosed |
| EP-0833631-A1 | BIFLAVANOIDS AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS | MEDICHEM RESEARCH, INC. (US) | 1998-04-08 | — | — | EP | disclosed |
| EP-0833631-A1 | BIFLAVANOIDS AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS | MEDICHEM RESEARCH, INC. (US) | 1998-04-08 | — | — | EP | disclosed |
| WO-1997000679-A1 | BIFLAVANOIDS AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS | MEDICHEM RESEARCH, INC. (US) | 1997-01-09 | — | — | WO | disclosed |
| WO-1997000679-A1 | BIFLAVANOIDS AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS | MEDICHEM RESEARCH, INC. (US) | 1997-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020068757-A1 | Biflavanoids and derivatives thereof as antiviral agents | HK2, GYS2, HK1 | APP 4657/4885MMP3 2628/4885MMP9 4056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.