Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.37 |
| ▸ | GCK | P35557 | 4/20 | 0.37 |
| ▸ | PDE4A | P27815 | 4/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14227757 | 0.94 | DHODH (0.39) | DHODHKCNH2GCKPDE4APDE4B | |
| SCHEMBL30078383 | 0.93 | DHODH (0.41) | DHODHKCNH2GCKPDE4APDE4B | |
| SCHEMBL563173 | 0.93 | DHODH (0.41) | DHODHKCNH2GCKPDE4APDE4B | |
| SCHEMBL15424655 | 0.93 | DHODH (0.39) | DHODHKCNH2GCKPDE4AKMT2A | |
| SCHEMBL29416604 | 0.90 | IDO1 (0.36) | DHODHKCNH2GCKIRAK4 | |
| SCHEMBL195661 | 0.90 | IDO1 (0.36) | DHODHKCNH2GCKIRAK4 | |
| SCHEMBL31256508 | 0.90 | DHODH (0.41) | DHODHKCNH2PDE4APKMCAPN1 | |
| SCHEMBL782468 | 0.90 | DHODH (0.41) | DHODHKCNH2PDE4APKMCAPN1 | |
| SCHEMBL10140235 | 0.86 | PDE4A (0.36) | DHODHKCNH2PDE4APDE4BPDE4C | |
| SCHEMBL10028777 | 0.85 | DHODH (0.40) | DHODHKCNH2PDE4AKMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247647-B2 | Cyano anthranilamide insecticides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-07-24 | — | — | US | claimed |
| US-9067892-B2 | Spiroheterocyclic N-oxypiperidines as pesticides | SYNGENTA CROP PROTECTION, INC. (US) | 2015-06-30 | — | — | US | disclosed |
| US-9067892-B2 | Spiroheterocyclic N-oxypiperidines as pesticides | SYNGENTA CROP PROTECTION, INC. (US) | 2015-06-30 | — | — | US | disclosed |
| US-8084474-B2 | Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-20110301031-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2011-12-08 | — | — | US | disclosed |
| US-20110301031-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2011-12-08 | — | — | US | disclosed |
| US-20100168066-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100168066-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168066-A1 | NOVEL INSECTICIDES | DDT, ACHE, CYP4F11 | DHODH 155/4885KCNH2 2025/4885GCK 3854/4885 |
| US-20110301031-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | DDT, THOP1, KCNH1 | DHODH 329/4885KCNH2 50/4885GCK 3334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.