Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 1/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.56 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.44 |
| ▸ | TACR1 | P25103 | 5/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.39 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL561532 | 0.91 | GABRA2 (0.46) | GABRA2GABRB2TLR8TACR1SLC6A4 | |
| SCHEMBL10567415 | 0.74 | PSMB5 (0.41) | TLR8PSDL3MBTL1HRH4 | |
| SCHEMBL17061916 | 0.73 | TACR1 (0.46) | GABRA2GABRB2TLR8TACR1SLC6A4 | |
| SCHEMBL561772 | 0.73 | ALDH1A1 (0.40) | GABRA2GABRB2TACR1SLC6A4KCNH2 | |
| SCHEMBL3564571 | 0.73 | MCHR1 (0.42) | GABRA2GABRB2MEN1ALDH1A1GAA | |
| SCHEMBL19771672 | 0.73 | HRH4 (0.41) | GABRA2GABRB2TLR8KCNH2PSD | |
| SCHEMBL3214532 | 0.73 | HRH4 (0.41) | GABRA2GABRB2TLR8KCNH2PSD | |
| SCHEMBL28282678 | 0.71 | NOS3 (0.46) | GABRA2GABRB2TLR8 | |
| SCHEMBL3229097 | 0.71 | HRH4 (0.42) | GABRA2GABRB2TLR8PSDL3MBTL1 | |
| SCHEMBL25405910 | 0.70 | CYP17A1 (0.41) | GABRA2GABRB2TLR8TACR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2420492-A1 | METHOD FOR PRODUCING 2-HALOGENO-6-SUBSTITUTED-4-TRIFLUOROMETHYLPYRIDINE | Ishihara Sangyo Kaisha, Ltd. (JP) | 2012-02-22 | — | — | EP | claimed |
| US-20120035372-A1 | METHOD FOR PRODUCING 2-HALOGENO-6-SUBSTITUTED-4-TRIFLUOROMETHYLPYRIDINE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2012-02-09 | — | — | US | claimed |
| EP-2420492-A1 | METHOD FOR PRODUCING 2-HALOGENO-6-SUBSTITUTED-4-TRIFLUOROMETHYLPYRIDINE | Ishihara Sangyo Kaisha, Ltd. (JP) | 2012-02-22 | — | — | EP | disclosed |
| US-20120035372-A1 | METHOD FOR PRODUCING 2-HALOGENO-6-SUBSTITUTED-4-TRIFLUOROMETHYLPYRIDINE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035372-A1 | METHOD FOR PRODUCING 2-HALOGENO-6-SUBSTITUTED-4-TRIFLUOROMETHYLPYRIDINE | RDX, CYP4X1, BRIX1 | GABRA2 1224/4885GABRB2 1854/4885TLR8 2499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.