SCHEMBL664705

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5622356	0.87	PGR (0.79)	PGRHPGDALDH1A1MAPTMEN1
	SCHEMBL15482244	0.85	HPGD (0.69)	PGRHPGDALDH1A1MAPTMEN1
	SCHEMBL665429	0.83	TAS2R14 (0.60)	PGRTAS2R14ALDH1A1PTGESTAS2R8
	SCHEMBL15953453	0.83	MAPK1 (0.69)	PGRALDH1A1MAPTMEN1KMT2A
	SCHEMBL11441218	0.83	MAPT (0.74)	TAS2R14HPGDALDH1A1MAPTMEN1
	SCHEMBL13190025	0.83	ALDH1A1 (0.62)	TAS2R14ALDH1A1MAPTMEN1KMT2A
	SCHEMBL10186886	0.83	L3MBTL1 (0.83)	PGRALDH1A1MAPTMEN1KMT2A
	SCHEMBL664209	0.83	CA12 (0.67)	TAS2R14ALDH1A1MAPTMEN1KMT2A
	SCHEMBL3718777	0.83	NR1I2 (0.62)	HPGDALDH1A1MAPTMEN1KMT2A
	SCHEMBL7267305	0.83	PGR (0.82)	PGRALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.