SCHEMBL5625535

SCHEMBL5625535

CCCCCCC(C)N(C)c1ccc(N(C)C(C)CCCCCC)cc1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.37
KDM4A O75164 2/20 0.36
KDM2A Q9Y2K7 2/20 0.36
SPHK1 Q9NYA1 1/20 0.35
LMNA P02545 1/20 0.34
HDAC11 Q96DB2 1/20 0.34
ADH1B P00325 1/20 0.33
ADH1C P00326 1/20 0.33
ADH1A P07327 1/20 0.33
ADH4 P08319 1/20 0.33
ADH7 P40394 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PLA2G1B P04054 1/20 0.33
PLA2G2A P14555 1/20 0.33
DNM1 Q05193 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11068432 0.88 CSNK1E (0.37) ALDH1A1
SCHEMBL12972981 0.87 TSHR (0.45)
SCHEMBL2258445 0.82 SIGMAR1 (0.39)
SCHEMBL7127555 0.81 KDM4A (0.44) KDM4AKDM2ALMNAHDAC11ALDH1A1
SCHEMBL12972982 0.79
SCHEMBL2991745 0.76 ALDH1A1 (0.42) OPRM1SPHK1ALDH1A1PLA2G1BPLA2G2A
SCHEMBL13227403 0.75 ESR1 (0.43) LMNAALDH1A1
SCHEMBL5226408 0.74 CSNK1E (0.42) ALDH1A1DNM1
SCHEMBL5223757 0.74 CSNK1E (0.42) ALDH1A1DNM1
SCHEMBL10879656 0.74 CSNK1E (0.40) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130310623-A1 AMINE GAS TREATMENT SOLUTIONS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2013-11-21 US disclosed
US-7199170-B2 Non-xenoestrogenic stabilizers for organic materials CROMPTON CORPORATION (US) 2007-04-03 US disclosed
US-20050080172-A1 Non-xenoestrogenic stabilizers for organic materials CK WITCO CORPORATION 2005-04-14 US disclosed
US-6858662-B2 Non-xenoestrogenic stabilizers for organic materials CROMPTON CORPORATION (US) 2005-02-22 US disclosed
US-20030096890-A1 Non-xenoestrogenic stabilizers for organic materials CROMPTON CORPORATION 2003-05-22 US disclosed
EP-1240245-A1 NON-XENOESTROGENIC PHOSPHITE STABILIZERS FOR ORGANIC MATERIALS Crompton Corporation (US) 2002-09-18 EP disclosed
EP-0635511-B1 Diphosphites as polymer stabilizers GEN ELECTRIC (US) 2001-11-28 EP disclosed
WO-2001032765-A1 NON-XENOESTROGENIC PHOSPHITE STABILIZERS FOR ORGANIC MATERIALS CROMPTON CORPORATION (US) 2001-05-10 WO disclosed
US-6180700-B1 Diphosphites GENERAL ELECTRIC COMPANY 2001-01-30 US disclosed
EP-0635513-B1 Neoalkyl alkylidene-2,2'-bisphenyl and biphenyl phosphite esters GEN ELECTRIC (US) 1999-04-21 EP disclosed
US-4094855-A Hindered phenyl phosphites CIBA-GEIGY CORPORATION (US) 1978-06-13 US disclosed
US-4069196-A Piperidyl esters of higher di-tri-, and polybasic aliphatic carboxylic acids as stabilizers for polymeric materials CIBA-GEIGY CORPORATION (US) 1978-01-17 US disclosed
US-4066616-A ORGANIC POLYMERS CIBA-GEIGY CORPORATION (US) 1978-01-03 US disclosed
US-4055539-A Alkylidene-bisphenols containing sulphur, and their use as stabilizers CIBA-GEIGY CORPORATION (US) 1977-10-25 US disclosed
US-4013619-A STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1977-03-22 US disclosed
US-3971803-A DISCOLORATION INHIBITION, POLYMER STABILIZERS CIBA-GEIGY CORPORATION (US) 1976-07-27 US disclosed
US-3959413-A POLYOLEFIN STABILIZERS CIBA-GEIGY CORPORATION (US) 1976-05-25 US disclosed
US-3956298-A POLYMER STABILIZERS CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed
US-3944632-A Phosphoric acid anilides CIBA-GEIGY CORPORATION (US) 1976-03-16 US disclosed
US-3943096-A Use of hydroxyphenylurethanes for stabilising elastomers CIBA-GEIGY CORPORATION (US) 1976-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130310623-A1 AMINE GAS TREATMENT SOLUTIONS GPX4, OAT, HNMT OPRM1 587/4885KDM4A 1710/4885KDM2A 2675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.