Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.42 |
| ▸ | CTSS | P25774 | 6/20 | 0.42 |
| ▸ | CTSB | P07858 | 4/20 | 0.42 |
| ▸ | CTSV | O60911 | 3/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | TRPV3 | Q8NET8 | 8/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | SI | P14410 | 4/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14384099 | 0.88 | CTSK (0.42) | CTSKCTSSCTSBCTSVCTSL | |
| SCHEMBL6403518 | 0.83 | CTSK (0.44) | CTSKCTSSCTSBCTSVCTSL | |
| SCHEMBL5631717 | 0.83 | CTSK (0.44) | CTSKCTSSCTSBCTSVCTSL | |
| SCHEMBL6406135 | 0.83 | CTSK (0.44) | CTSKCTSSCTSBCTSVCTSL | |
| SCHEMBL14405047 | 0.80 | ACSS2 (0.43) | CTSKCTSSCTSBCTSVCTSL | |
| SCHEMBL28825602 | 0.76 | ALDH1A1 (0.51) | KCNH2 | |
| SCHEMBL5630373 | 0.75 | KCNH2 (0.40) | CTSKCTSSCTSBCTSVCTSL | |
| SCHEMBL5630369 | 0.74 | ALDH1A1 (0.39) | CTSKCTSSCTSBCTSVCTSL | |
| SCHEMBL2629316 | 0.73 | KEAP1 (0.58) | KCNH2 | |
| SCHEMBL31128117 | 0.72 | ALDH1A1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7288541-B2 | Propylcarbamate derivatives as inhibitors of serine and cysteine proteases | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-30 | — | — | US | disclosed |
| US-20050043368-A1 | Propylcarbamate derivatives as inhibitors of serine and cysteine proteases | SMITHKLINE BEECHAM CORPORATION | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043368-A1 | Propylcarbamate derivatives as inhibitors of serine and cysteine proteases | CTSK, CTSB, CTSS | CTSK 1/4885CTSS 3/4885CTSB 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.