Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | STK17B | O94768 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25687336 | 0.79 | FLT3 (0.62) | FLT3NPC1RAB9AMAPK1TSHR | |
| SCHEMBL29496924 | 0.79 | FLT3 (0.74) | FLT3NPC1RAB9AMAPK1TSHR | |
| SCHEMBL649402 | 0.79 | FLT3 (0.74) | FLT3NPC1RAB9AMAPK1TSHR | |
| SCHEMBL7825736 | 0.79 | FLT3 (0.56) | FLT3NPC1RAB9AMAPK1TSHR | |
| Hydrochloric Acid SCHEMBL5981164 | 0.78 | FLT3 (0.71) | FLT3NPC1RAB9AMAPK1TSHR | |
| SCHEMBL826292 | 0.78 | FLT3 (0.71) | FLT3NPC1RAB9AMAPK1TSHR | |
| Hydrochloric Acid SCHEMBL27610018 | 0.78 | FLT3 (0.71) | FLT3NPC1RAB9AMAPK1TSHR | |
| Hydrochloric Acid SCHEMBL30722382 | 0.78 | FLT3 (0.71) | FLT3NPC1RAB9AMAPK1TSHR | |
| SCHEMBL31061078 | 0.77 | FLT3 (1.00) | FLT3NPC1RAB9AMAPK1TSHR | |
| SCHEMBL8915455 | 0.77 | FLT3 (0.64) | FLT3NPC1RAB9AMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230255969-A1 | TARGETING IMMUNE PATHOLOGIES INDUCED BY HIGHLY PATHOGENIC CORONAVIRUSES | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2023-08-17 | — | — | US | claimed |
| EP-4185286-A1 | TARGETING IMMUNE PATHOLOGIES INDUCED BY HIGHLY PATHOGENIC CORONAVIRUSES | National University of Singapore (SG) | 2023-05-31 | — | — | EP | claimed |
| WO-2022019828-A1 | TARGETING IMMUNE PATHOLOGIES INDUCED BY HIGHLY PATHOGENIC CORONAVIRUSES | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2022-01-27 | — | — | WO | claimed |
| US-8691859-B2 | Broad spectrum antibacterial compounds | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2014-04-08 | — | — | US | claimed |
| US-20110086877-A1 | Small Molecule Inhibitors of Botulinum Neurotoxins | BAVARI SINA | 2011-04-14 | — | — | US | claimed |
| EP-1689732-A4 | CATIONIC SUBSTITUTED BENZOFURANS AS ANTIMICROBIAL AGENTS | UNIV NORTH CAROLINA (US) | 2008-10-22 | — | — | EP | claimed |
| US-20080221191-A1 | Cationic substituted benzofurans as antimicrobial agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-09-11 | — | — | US | claimed |
| US-20080114047-A1 | Cationic substituted benzofurans as antimicrobial agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-05-15 | — | — | US | claimed |
| US-20070112048-A1 | Broad Spectrum Antibacterial Compounds | U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND | 2007-05-17 | — | — | US | claimed |
| US-20070112049-A1 | nonpeptidic inhibitors of Botulinum neurotoxin A metalloprotease activity, such as 2-[4-(4-carbamimidoylphenoxy)phenyl]-1H-indole-5-carboximidamide, used for treating, inhibiting or preventing intoxication caused by bacteria | ARMY, UNITED STATES | 2007-05-17 | — | — | US | claimed |
| EP-1689732-A2 | CATIONIC SUBSTITUTED BENZOFURANS AS ANTIMICROBIAL AGENTS | The University of North Carolina at Chapel Hill (US) | 2006-08-16 | — | — | EP | claimed |
| US-20050197378-A1 | Cationic substituted benzofurans as antimicrobial agents | TIDWELL RICHARD R (US) | 2005-09-08 | — | — | US | claimed |
| WO-2005055935-A2 | CATIONIC SUBSTITUTED BENZOFURANS AS ANTIMICROBIAL AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2005-06-23 | — | — | WO | claimed |
| EP-0906301-B1 | BENZOFURYL DERIVATIVES AND THEIR USE | HOFFMANN LA ROCHE (CH) | 2002-10-02 | — | — | EP | claimed |
| EP-0906301-A1 | BENZOFURYL DERIVATIVES AND THEIR USE | F. HOFFMANN-LA ROCHE AG (CH) | 1999-04-07 | — | — | EP | claimed |
| WO-1997042183-A1 | BENZOFURYL DERIVATIVES AND THEIR USE | F. HOFFMANN-LA ROCHE AG (CH) | 1997-11-13 | — | — | WO | claimed |
| US-20230255969-A1 | TARGETING IMMUNE PATHOLOGIES INDUCED BY HIGHLY PATHOGENIC CORONAVIRUSES | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2023-08-17 | — | — | US | disclosed |
| EP-4185286-A1 | TARGETING IMMUNE PATHOLOGIES INDUCED BY HIGHLY PATHOGENIC CORONAVIRUSES | National University of Singapore (SG) | 2023-05-31 | — | — | EP | disclosed |
| CN-1168886-A | Process for production of amidinobenzofuran and amidionbenzothiophen derivatives and salt thereof | DAIICHI SEIYAKU CO (JP) | 1997-12-31 | — | — | CN | disclosed |
| WO-1997042183-A1 | BENZOFURYL DERIVATIVES AND THEIR USE | F. HOFFMANN-LA ROCHE AG (CH) | 1997-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080114047-A1 | Cationic substituted benzofurans as antimicrobial agents | BET1, ARG2, BRDT | FLT3 1964/4885NPC1 386/4885RAB9A 2992/4885 |
| US-20070112048-A1 | Broad Spectrum Antibacterial Compounds | MPO, CAT, LPO | FLT3 4851/4885NPC1 1097/4885RAB9A 725/4885 |
| US-20050197378-A1 | Cationic substituted benzofurans as antimicrobial agents | BET1, ARG2, BRDT | FLT3 1964/4885NPC1 386/4885RAB9A 2992/4885 |
| US-20080221191-A1 | Cationic substituted benzofurans as antimicrobial agents | BET1, ARG2, BRDT | FLT3 1964/4885NPC1 386/4885RAB9A 2992/4885 |
| US-20070112049-A1 | nonpeptidic inhibitors of Botulinum neurotoxin A metalloprotease activity, such as 2-[4-(4-carbamimidoylphenoxy)phenyl]-1H-indole-5-carboximidamide, used for treating, inhibiting or preventing intoxication caused by bacteria | ACHE, CTRL, MMP2 | FLT3 4860/4885NPC1 2813/4885RAB9A 1334/4885 |
| US-20110086877-A1 | Small Molecule Inhibitors of Botulinum Neurotoxins | ACHE, MMP2, TIMP3 | FLT3 4875/4885NPC1 2858/4885RAB9A 634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.